Endocytosed HSP60s use toll-like receptor 2 (TLR2) and TLR4 to activate the toll/interleukin-1 receptor signaling pathway in innate immune cells RM Vabulas, P Ahmad-Nejad, C da Costa, T Miethke, CJ Kirschning, ... Journal of Biological Chemistry 276 (33), 31332-31339, 2001 | 1083 | 2001 |
The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway RM Vabulas, S Braedel, N Hilf, H Singh-Jasuja, S Herter, P Ahmad-Nejad, ... Journal of Biological Chemistry 277 (23), 20847-20853, 2002 | 634 | 2002 |
CD25+/Foxp3+ T cells regulate gastric inflammation and Helicobacter pylori colonization in vivo R Rad, L Brenner, S Bauer, S Schwendy, L Layland, CP da Costa, ... Gastroenterology 131 (2), 525-537, 2006 | 349 | 2006 |
Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses M Ritter, O Gross, S Kays, J Ruland, F Nimmerjahn, S Saijo, J Tschopp, ... Proceedings of the National Academy of Sciences 107 (47), 20459-20464, 2010 | 291 | 2010 |
Predominant role of toll-like receptor 2 versus 4 in Chlamydia pneumoniae-induced activation of dendritic cells S Prebeck, C Kirschning, S Durr, C da Costa, B Donath, K Brand, ... The Journal of Immunology 167 (6), 3316-3323, 2001 | 255 | 2001 |
Treatment of Chlamydia pneumoniae infection with roxithromycin and effect on neointima proliferation after coronary stent placement (ISAR-3): a randomised, double-blind … FJ Neumann, A Kastrati, T Miethke, G Pogatsa-Murray, J Mehilli, C Valina, ... The Lancet 357 (9274), 2085-2089, 2001 | 169 | 2001 |
Immunopathology in schistosomiasis is controlled by antigen‐specific regulatory T cells primed in the presence of TLR2 LE Layland, R Rad, H Wagner, CUP Da Costa European journal of immunology 37 (8), 2174-2184, 2007 | 166 | 2007 |
The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling C Desel, K Werninghaus, M Ritter, K Jozefowski, J Wenzel, N Russkamp, ... PloS one 8 (1), e53531, 2013 | 156 | 2013 |
Helicobacter pylori–induced IL-1β secretion in innate immune cells is regulated by the NLRP3 Inflammasome and requires the cag Pathogenicity Island RP Semper, R Mejías-Luque, C Groß, F Anderl, A Müller, M Vieth, ... The Journal of Immunology 193 (7), 3566-3576, 2014 | 124 | 2014 |
Pronounced phenotype in activated regulatory T cells during a chronic helminth infection LE Layland, J Mages, C Loddenkemper, A Hoerauf, H Wagner, R Lang, ... The journal of immunology 184 (2), 713-724, 2010 | 109 | 2010 |
Microbes and asthma: opportunities for intervention HH Smits, PS Hiemstra, CP Da Costa, M Ege, M Edwards, H Garn, ... Journal of Allergy and Clinical Immunology 137 (3), 690-697, 2016 | 105 | 2016 |
Schistosoma mansoni-Mediated Suppression of Allergic Airway Inflammation Requires Patency and Foxp3+ Treg Cells LE Layland, K Straubinger, M Ritter, E Loffredo-Verde, H Garn, ... PLoS neglected tropical diseases 7 (8), e2379, 2013 | 87 | 2013 |
Dectin-1/2–induced autocrine PGE2 signaling licenses dendritic cells to prime Th2 responses MMM Kaisar, M Ritter, C Del Fresno, HS Jónasdóttir, AJ van der Ham, ... PLoS biology 16 (4), e2005504, 2018 | 84 | 2018 |
Vav proteins are key regulators of Card9 signaling for innate antifungal immunity S Roth, H Bergmann, M Jaeger, A Yeroslaviz, K Neumann, PA Koenig, ... Cell reports 17 (10), 2572-2583, 2016 | 78 | 2016 |
Maternal immune response to helminth infection during pregnancy determines offspring susceptibility to allergic airway inflammation K Straubinger, S Paul, OP da Costa, M Ritter, T Buch, DH Busch, ... Journal of allergy and clinical immunology 134 (6), 1271-1279. e10, 2014 | 74 | 2014 |
Antimicrobial resistance in livestock and poor quality veterinary medicines K Clifford, D Desai, CP da Costa, H Meyer, K Klohe, AS Winkler, ... Bulletin of the World Health Organization 96 (9), 662, 2018 | 72 | 2018 |
Lack of host gut microbiota alters immune responses and intestinal granuloma formation during schistosomiasis M Holzscheiter, LE Layland, E Loffredo-Verde, K Mair, R Vogelmann, ... Clinical & Experimental Immunology 175 (2), 246-257, 2014 | 70 | 2014 |
Fetal–maternal alignment of regulatory T cells correlates with IL-10 and Bcl-2 upregulation in pregnancy B Santner-Nanan, K Straubinger, P Hsu, G Parnell, B Tang, B Xu, ... The Journal of Immunology 191 (1), 145-153, 2013 | 70 | 2013 |
Lack of antigen‐specific Th1 response alters granuloma formation and composition in Schistosoma mansoni‐infected MyD88–/– mice LE Layland, H Wagner, CU Prazeres da Costa European journal of immunology 35 (11), 3248-3257, 2005 | 67 | 2005 |
The Gram-negative bacterium Chlamydia trachomatis L2 stimulates tumor necrosis factor secretion by innate immune cells independently of its endotoxin S Prebeck, H Brade, CJ Kirschning, CP da Costa, S Dürr, H Wagner, ... Microbes and infection 5 (6), 463-470, 2003 | 66 | 2003 |