Maria Paola COSTI
Maria Paola COSTI
Tuntematon yhteys
Vahvistettu sähköpostiosoite verkkotunnuksessa unimore.it
NimikeViittauksetVuosi
Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development
A Cavazzuti, G Paglietti, WN Hunter, F Gamarro, S Piras, M Loriga, ...
Proceedings of the National Academy of Sciences 105 (5), 1448-1453, 2008
1012008
Discovery of highly potent acid ceramidase inhibitors with in vitro tumor chemosensitizing activity
N Realini, C Solorzano, C Pagliuca, D Pizzirani, A Armirotti, R Luciani, ...
Scientific reports 3, 1035, 2013
902013
The Hippo pathway and YAP/TAZ–TEAD protein–protein interaction as targets for regenerative medicine and cancer treatment: Miniperspective
M Santucci, T Vignudelli, S Ferrari, M Mor, L Scalvini, ML Bolognesi, ...
Journal of medicinal chemistry 58 (12), 4857-4873, 2015
862015
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1
J Neres, RC Hartkoorn, LR Chiarelli, R Gadupudi, MR Pasca, G Mori, ...
ACS chemical biology 10 (3), 705-714, 2014
642014
Structure-based design and in-parallel synthesis of inhibitors of AmpC β-lactamase
D Tondi, RA Powers, E Caselli, MC Negri, J Blázquez, MP Costi, ...
Chemistry & biology 8 (6), 593-610, 2001
632001
Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase
S Ferrari, F Morandi, D Motiejunas, E Nerini, S Henrich, R Luciani, ...
Journal of medicinal chemistry 54 (1), 211-221, 2010
552010
Optimizing cell permeation of an antibiotic resistance inhibitor for improved efficacy
A Venturelli, D Tondi, L Cancian, F Morandi, G Cannazza, B Segatore, ...
Journal of medicinal chemistry 50 (23), 5644-5654, 2007
472007
Structural study of phenyl boronic acid derivatives as AmpC β-lactamase inhibitors
D Tondi, S Calò, BK Shoichet, MP Costi
Bioorganic & medicinal chemistry letters 20 (11), 3416-3419, 2010
432010
Thymidylate synthase inhibition: A structure‐based rationale for drug design
MP Costi
Medicinal research reviews 18 (1), 21-42, 1998
331998
Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance
L Taddia, D D’Arca, S Ferrari, C Marraccini, L Severi, G Ponterini, ...
Drug Resistance Updates 23, 20-54, 2015
322015
Profiling of flavonol derivatives for the development of antitrypanosomatidic drugs
C Borsari, R Luciani, C Pozzi, I Poehner, S Henrich, M Trande, ...
Journal of medicinal chemistry 59 (16), 7598-7616, 2016
302016
Quinoxaline chemistry. Part 15. 4-[2-Quinoxalylmethylenimino]-benzoylglutamates and-benzoates, 4-[2-quinoxalylmethyl-N-methylamino]-benzoylglutamates as analogues of classical …
M Loriga, S Piras, G Paglietti, MP Costi, A Venturelli
Il Farmaco 58 (1), 51-61, 2003
302003
Targeting class A and C serine β-lactamases with a broad-spectrum boronic acid derivative
D Tondi, A Venturelli, R Bonnet, C Pozzi, BK Shoichet, MP Costi
Journal of medicinal chemistry 57 (12), 5449-5458, 2014
292014
Current and future chemotherapy for Chagas disease
L Gaspar, C B Moraes, L H Freitas-Junior, S Ferrari, L Costantino, ...
Current medicinal chemistry 22 (37), 4293-4312, 2015
282015
Quinoxaline chemistry. Part 11. 3-Phenyl-2 [phenoxy-and phenoxymethyl]-6 (7) or 6, 8-substituted quinoxalines and N-[4-(6 (7)-substituted or 6, 8-disubstituted-3 …
P Corona, G Vitale, M Loriga, G Paglietti, MP Costi
Il Farmaco 53 (7), 480-493, 1998
281998
Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and-resistant human ovarian cancer cells
G Marverti, A Ligabue, P Lombardi, S Ferrari, MG Monti, C Frassineti, ...
International Journal of Oncology 43 (4), 1269-1280, 2013
272013
Novel 3‐benzoyl‐2‐piperazinylquinoxaline derivatives as potential antitumor agents
S Piras, M Loriga, A Carta, G Paglietti, M Paola Costi, S Ferrari
Journal of heterocyclic chemistry 43 (3), 541-548, 2006
252006
The inhibition of extended spectrum β-lactamases: hits and leads
D Farina, F Spyrakis, A Venturelli, S Cross, D Tondi, M Paola Costi
Current medicinal chemistry 21 (12), 1405-1434, 2014
232014
Ligand-based virtual screening and ADME-tox guided approach to identify triazolo-quinoxalines as folate cycle inhibitors
E Carosati, G Sforna, M Pippi, G Marverti, A Ligabue, D Guerrieri, S Piras, ...
Bioorganic & medicinal chemistry 18 (22), 7773-7785, 2010
232010
Collateral sensitivity to novel thymidylate synthase inhibitors correlates with folate cycle enzymes impairment in cisplatin-resistant human ovarian cancer cells
G Marverti, A Ligabue, G Paglietti, P Corona, S Piras, G Vitale, D Guerrieri, ...
European journal of pharmacology 615 (1-3), 17-26, 2009
232009
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Artikkelit 1–20