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Trevor Fidler
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The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
TP Fidler, C Xue, M Yalcinkaya, B Hardaway, S Abramowicz, T Xiao, ...
Nature 592 (7853), 296-301, 2021
2732021
Macrophage Inflammation, Erythrophagocytosis, and Accelerated Atherosclerosis in Jak2V617F Mice
W Wang, W Liu, T Fidler, Y Wang, Y Tang, B Woods, C Welch, B Cai, ...
Circulation research 123 (11), e35-e47, 2018
2062018
SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis
Y Zhang, L Xie, SK Gunasekar, D Tong, A Mishra, WJ Gibson, C Wang, ...
Nature cell biology 19 (5), 504-517, 2017
1322017
Deletion of GLUT1 and GLUT3 reveals multiple roles for glucose metabolism in platelet and megakaryocyte function
TP Fidler, RA Campbell, T Funari, N Dunne, EB Angeles, EA Middleton, ...
Cell reports 20 (4), 881-894, 2017
842017
Metabolic pathways of inhaled glucocorticoids by the CYP3A enzymes
CD Moore, JK Roberts, CR Orton, T Murai, TP Fidler, CA Reilly, RM Ward, ...
Drug Metabolism and Disposition 41 (2), 379-389, 2013
812013
Loss of MCU prevents mitochondrial fusion in G1-S phase and blocks cell cycle progression and proliferation
OM Koval, EK Nguyen, V Santhana, TP Fidler, SC Sebag, TP Rasmussen, ...
Science signaling 12 (579), eaav1439, 2019
612019
Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein
M Yalcinkaya, W Liu, MN Islam, AG Kotini, GA Gusarova, TP Fidler, ...
Scientific reports 11 (1), 24432, 2021
592021
Oxidized phospholipids promote NETosis and arterial thrombosis in LNK (SH2B3) deficiency
H Dou, A Kotini, W Liu, T Fidler, K Endo-Umeda, X Sun, M Olszewska, ...
Circulation 144 (24), 1940-1954, 2021
412021
Glucose metabolism is required for platelet hyperactivation in a murine model of type 1 diabetes
TP Fidler, A Marti, K Gerth, EA Middleton, RA Campbell, MT Rondina, ...
Diabetes 68 (5), 932-938, 2019
392019
Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis
W Liu, N Östberg, M Yalcinkaya, H Dou, K Endo-Umeda, Y Tang, X Hou, ...
The Journal of clinical investigation 132 (13), 2022
382022
Inhibition of JAK2 Suppresses Myelopoiesis and Atherosclerosis in Apoe−/− Mice
Y Tang, W Liu, W Wang, T Fidler, B Woods, RL Levine, AR Tall, N Wang
Cardiovascular drugs and therapy 34, 145-152, 2020
372020
Improved coiled-coil design enhances interaction with Bcr-Abl and induces apoptosis
AS Dixon, GD Miller, BJ Bruno, JE Constance, DW Woessner, TP Fidler, ...
Molecular pharmaceutics 9 (1), 187-195, 2012
352012
Glucose transporter 3 potentiates degranulation and is required for platelet activation
TP Fidler, EA Middleton, JW Rowley, LH Boudreau, RA Campbell, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (9), 1628-1639, 2017
342017
Superoxide Dismutase 2 is dispensable for platelet function
TP Fidler, JW Rowley, C Araujo, LH Boudreau, A Marti, R Souvenir, ...
Thrombosis and haemostasis 117 (10), 1859-1867, 2017
242017
Cytochrome P450 2S1 depletion enhances cell proliferation and migration in bronchial epithelial cells, in part, through modulation of prostaglandin E2 synthesis
TW Madanayake, TP Fidler, TM Fresquez, N Bajaj, AM Rowland
Drug Metabolism and Disposition 40 (11), 2119-2125, 2012
232012
Endogenous SOD2 (superoxide dismutase) regulates platelet-dependent thrombin generation and thrombosis during aging
VK Sonkar, AS Eustes, A Ahmed, M Jensen, MV Solanki, J Swamy, ...
Arteriosclerosis, thrombosis, and vascular biology 43 (1), 79-91, 2023
102023
Genetic modification of inflammation-and clonal hematopoiesis–associated cardiovascular risk
Z Yu, TP Fidler, Y Ruan, C Vlasschaert, T Nakao, MM Uddin, T Mack, ...
The Journal of Clinical Investigation 133 (18), 2023
92023
Hematopoietic NLRP3 and AIM2 inflammasomes promote diabetes-accelerated atherosclerosis, but increased necrosis is independent of pyroptosis
CC Hsu, TP Fidler, JE Kanter, V Kothari, F Kramer, J Tang, AR Tall, ...
Diabetes 72 (7), 999-1011, 2023
82023
Suppression of IL-1β promotes beneficial accumulation of fibroblast-like cells in atherosclerotic plaques in clonal hematopoiesis
TP Fidler, A Dunbar, E Kim, B Hardaway, J Pauli, C Xue, S Abramowicz, ...
Nature cardiovascular research, 1-16, 2024
32024
Correction to “improved coiled-coil design enhances interaction with bcr-abl and induces apoptosis”
AS Dixon, GD Miller, BJ Bruno, JE Constance, DW Woessner, TP Fidler, ...
Molecular pharmaceutics 9 (5), 1535-1535, 2012
12012
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