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Heikki Hyöty
Heikki Hyöty
Tampere University, Finland
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The dynamics of the human infant gut microbiome in development and in progression toward type 1 diabetes
AD Kostic, D Gevers, H Siljander, T Vatanen, T Hyötyläinen, ...
Cell host & microbe 17 (2), 260-273, 2015
11902015
Toward defining the autoimmune microbiome for type 1 diabetes
A Giongo, KA Gano, DB Crabb, N Mukherjee, LL Novelo, G Casella, ...
The ISME journal 5 (1), 82-91, 2011
9452011
Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes
CT Brown, AG Davis-Richardson, A Giongo, KA Gano, DB Crabb, ...
PloS one 6 (10), e25792, 2011
8642011
Environmental triggers and determinants of type 1 diabetes
M Knip, R Veijola, SM Virtanen, H Hyoty, O Vaarala, HK Akerblom
Diabetes 54 (suppl_2), S125-S136, 2005
7172005
Environmental factors in the etiology of type 1 diabetes
HK Åkerblom, O Vaarala, H Hyöty, J Ilonen, M Knip
American journal of medical genetics 115 (1), 18-29, 2002
5072002
Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes
M Oresic, S Simell, M Sysi-Aho, K Nanto-Salonen, T Seppanen-Laakso, ...
The Journal of experimental medicine 205 (13), 2975-2984, 2008
4982008
Nasal insulin to prevent type 1 diabetes in children with HLA genotypes and autoantibodies conferring increased risk of disease: a double-blind, randomised controlled trial
K Näntö-Salonen, A Kupila, S Simell, H Siljander, T Salonsaari, ...
The Lancet 372 (9651), 1746-1755, 2008
4232008
The role of viruses in human diabetes
H Hyöty, K Taylor
Diabetologia 45, 1353-1361, 2002
4082002
Enterovirus infection as a risk factor for beta-cell autoimmunity in a prospectively observed birth cohort: the Finnish Diabetes Prediction and Prevention Study.
M Lönnrot, K Korpela, M Knip, J Ilonen, O Simell, S Korhonen, K Savola, ...
Diabetes 49 (8), 1314-1318, 2000
3782000
Strain-level analysis of mother-to-child bacterial transmission during the first few months of life
M Yassour, E Jason, LJ Hogstrom, TD Arthur, S Tripathi, H Siljander, ...
Cell host & microbe 24 (1), 146-154. e4, 2018
3572018
Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes
L Krogvold, B Edwin, T Buanes, G Frisk, O Skog, M Anagandula, ...
Diabetes 64 (5), 1682-1687, 2015
3462015
Coxsackievirus B1 is associated with induction of β-cell autoimmunity that portends type 1 diabetes
OH Laitinen, H Honkanen, O Pakkanen, S Oikarinen, MM Hankaniemi, ...
Diabetes 63 (2), 446-455, 2014
3272014
Aberrant gut microbiota composition at the onset of type 1 diabetes in young children
MC de Goffau, S Fuentes, B Van Den Bogert, H Honkanen, WM de Vos, ...
Diabetologia 57, 1569-1577, 2014
3232014
The Environmental Determinants of Diabetes in the Young (TEDDY) study: study design
TEDDY Study Group
Pediatric diabetes 8 (5), 286-298, 2007
3022007
Bacteroides dorei dominates gut microbiome prior to autoimmunity in Finnish children at high risk for type 1 diabetes
AG Davis-Richardson, AN Ardissone, R Dias, V Simell, MT Leonard, ...
Frontiers in microbiology 5, 678, 2014
2872014
Rectal bleeding in infancy: clinical, allergological, and microbiological examination
T Arvola, T Ruuska, J Keränen, H Hyöty, S Salminen, E Isolauri
Pediatrics 117 (4), e760-e768, 2006
2862006
A prospective study of the role of coxsackie B and other enterovirus infections in the pathogenesis of IDDM
H Hyöty, M Hiltunen, M Knip, M Laakkonen, P Vähäsalo, J Karjalainen, ...
Diabetes 44 (6), 652-657, 1995
2821995
Enterovirus infection and progression from islet autoimmunity to type 1 diabetes: the Diabetes and Autoimmunity Study in the Young (DAISY)
LC Stene, S Oikarinen, H Hyöty, KJ Barriga, JM Norris, G Klingensmith, ...
Diabetes 59 (12), 3174-3180, 2010
2782010
Early seroconversion and rapidly increasing autoantibody concentrations predict prepubertal manifestation of type 1 diabetes in children at genetic risk
V Parikka, K Näntö-Salonen, M Saarinen, T Simell, J Ilonen, H Hyöty, ...
Diabetologia 55, 1926-1936, 2012
2762012
Epidemiology of childhood diabetes mellitus in Finland—background of a nationwide study of type 1 (insulin-dependent) diabetes mellitus
J Tuomilehto, R Lounamaa, E Tuomilehto-Wolf, A Reunanen, E Virtala, ...
Diabetologia 35, 70-76, 1992
2491992
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