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Harikrishna Sekar Jayanthan
Harikrishna Sekar Jayanthan
Evotec UK Ltd
Verified email at evotec.com
Title
Cited by
Cited by
Year
Thioflavin T as an efficient inducer and selective fluorescent sensor for the human telomeric G-quadruplex DNA
J Mohanty, N Barooah, V Dhamodharan, S Harikrishna, PI Pradeepkumar, ...
Journal of the American Chemical Society 135 (1), 367-376, 2013
6112013
Selective G-quadruplex DNA stabilizing agents based on bisquinolinium and bispyridinium derivatives of 1, 8-naphthyridine
V Dhamodharan, S Harikrishna, C Jagadeeswaran, K Halder, ...
The Journal of organic chemistry 77 (1), 229-242, 2012
772012
Specific Stabilization of c-MYC and c-KIT G-Quadruplex DNA Structures by Indolylmethyleneindanone Scaffolds
KV Diveshkumar, S Sakrikar, F Rosu, S Harikrishna, V Gabelica, ...
Biochemistry 55 (25), 3571-3585, 2016
632016
Topology specific stabilization of promoter over telomeric G-quadruplex DNAs by bisbenzimidazole carboxamide derivatives
V Dhamodharan, S Harikrishna, AC Bhasikuttan, PI Pradeepkumar
ACS chemical biology 10 (3), 821-833, 2015
582015
Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity
AB Hanker, BP Brown, J Meiler, A Marín, HS Jayanthan, D Ye, CC Lin, ...
Cancer cell 39 (8), 1099-1114. e8, 2021
502021
Targeting Promoter G‐Quadruplex DNAs by Indenopyrimidine‐Based Ligands
KV Diveshkumar, S Sakrikar, S Harikrishna, V Dhamodharan, ...
ChemMedChem 9 (12), 2754-2765, 2014
442014
Synthesis, Gene Silencing, and Molecular Modeling Studies of 4′-C-Aminomethyl-2′-O-methyl Modified Small Interfering RNAs
KR Gore, GN Nawale, S Harikrishna, VG Chittoor, SK Pandey, ...
The Journal of Organic Chemistry 77 (7), 3233-3245, 2012
372012
Influence of 2′-Fluoro versus 2′-O-Methyl Substituent on the Sugar Puckering of 4′-C-Aminomethyluridine
KR Gore, S Harikrishna, PI Pradeepkumar
The Journal of Organic Chemistry 78 (19), 9956-9962, 2013
312013
Probing the binding interactions between chemically modified siRNAs and human argonaute 2 using microsecond molecular dynamics simulations
S Harikrishna, PI Pradeepkumar
Journal of Chemical Information and Modeling 57 (4), 883-896, 2017
222017
Ligand-induced conformational preorganization of loops of c-MYC G-quadruplex DNA and its implications in structure-specific drug design
S Harikrishna, S Kotaru, PI Pradeepkumar
Molecular BioSystems 13 (8), 1458-1468, 2017
182017
The N2-Furfuryl-deoxyguanosine Adduct Does Not Alter the Structure of B-DNA
PP Ghodke, KR Gore, S Harikrishna, B Samanta, J Kottur, DT Nair, ...
The Journal of Organic Chemistry 81 (2), 502-511, 2016
172016
Effect of 2′-5′/3′-5′ phosphodiester linkage heterogeneity on RNA interference
M Habibian, S Harikrishna, J Fakhoury, M Barton, EA Ageely, R Cencic, ...
Nucleic Acids Research 48 (9), 4643-4657, 2020
162020
Synthesis and Polymerase-Mediated Bypass Studies of the N2-Deoxyguanosine DNA Damage Caused by a Lucidin Analogue
PP Ghodke, S Harikrishna, PI Pradeepkumar
The Journal of Organic Chemistry 80 (4), 2128-2138, 2015
162015
Influence of Sugar Modifications on the Nucleoside Conformation and Oligonucleotide Stability: A Critical Review
G Das, S Harikrishna, KR Gore
The Chemical Record 22 (12), e202200174, 2022
52022
Nucleoside Analogues with a seven-membered sugar ring: synthesis and structural compatibility in DNA–RNA hybrids
SK Jana, S Harikrishna, S Sudhakar, R El-Khoury, PI Pradeepkumar, ...
The Journal of Organic Chemistry 87 (5), 2367-2379, 2022
52022
Synthesis, Structural, and Conformational Analysis of 4′‐C‐Alkyl‐2′‐O‐Ethyl‐Uridine Modified Nucleosides
RR Nikam, S Harikrishna, KR Gore
European Journal of Organic Chemistry 2021 (6), 924-932, 2021
52021
Synthesis and Structural Analysis of N3‐Methyluridine and 2’‐Alkoxy/Fluoro‐N3‐Methyluridine Nucleosides by Using NMR Spectroscopy, X‐Ray …
A Sahoo, G Das, NK Choudhary, S Harikrishna, KR Gore
ChemistrySelect 8 (24), e202301858, 2023
22023
Co-Occurring Gain-of-Function Mutations in HER2 and HER3 Modulate HER2/HER3 Activation, Breast Cancer Progression, and HER2 Inhibitor Sensitivity
A Hanker, S Harikrishna, A Marin, D Ye, CC Lin, DR Sudhan, H Akamatsu, ...
Breast Cancer Progression, and HER2 Inhibitor Sensitivity, 2020
22020
Abstract GS6-04: Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, breast cancer progression, and HER2 inhibitor sensitivity
AB Hanker, HS Jayanthan, D Ye, CC Lin, H Akamatsu, JH Sheehan, ...
Cancer Research 80 (4_Supplement), GS6-04-GS6-04, 2020
12020
4′-C-Acetamidomethyl-2′-O-methoxyethyl Nucleic Acid Modifications Improve Thermal Stability, Nuclease Resistance, Potency, and hAgo2 Binding of Small …
S Gangopadhyay, G Das, S Gupta, A Ghosh, SS Bagale, PK Roy, ...
The Journal of Organic Chemistry, 2024
2024
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