J.T. Neal
J.T. Neal
Broad Institute of MIT and Harvard
Verified email at broadinstitute.org - Homepage
Title
Cited by
Cited by
Year
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis
J Rosenbluh, D Nijhawan, AG Cox, X Li, JT Neal, EJ Schafer, TI Zack, ...
Cell 151 (7), 1457-1473, 2012
5892012
Organoid modeling of the tumor immune microenvironment
JT Neal, X Li, J Zhu, V Giangarra, CL Grzeskowiak, J Ju, IH Liu, SH Chiou, ...
Cell 175 (7), 1972-1988. e16, 2018
3202018
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture
X Li, L Nadauld, A Ootani, DC Corney, RK Pai, O Gevaert, MA Cantrell, ...
Nature medicine 20 (7), 769, 2014
2402014
Epithelial cell proliferation in the developing zebrafish intestine is regulated by the Wnt pathway and microbial signaling via Myd88
SE Cheesman, JT Neal, E Mittge, BM Seredick, K Guillemin
Proceedings of the National Academy of Sciences 108 (Supplement 1), 4570-4577, 2011
1752011
H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model
JT Neal, TS Peterson, ML Kent, K Guillemin
Disease models & mechanisms 6 (3), 802-810, 2013
932013
Organoids as models for neoplastic transformation
JT Neal, CJ Kuo
Annual Review of Pathology: Mechanisms of Disease 11, 199-220, 2016
442016
The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein
L Chakrabarti, JT Neal, M Miles, RA Martinez, AC Smith, BL Sopher, ...
Mammalian genome 17 (2), 103-110, 2006
322006
Identification of genetic modifiers of CagA-induced epithelial disruption in Drosophila
DW Reid, JB Muyskens, JT Neal, GW Gaddini, LY Cho, AM Wandler, ...
Frontiers in cellular and infection microbiology 2, 24, 2012
132012
Massively parallel assessment of human variants with base editor screens
RE Hanna, M Hegde, CR Fagre, PC DeWeirdt, AK Sangree, Z Szegletes, ...
Cell 184 (4), 1064-1080. e20, 2021
92021
Massively parallel phenotyping of variant impact in cancer with Perturb-seq reveals a shift in the spectrum of cell states induced by somatic mutations
O Ursu, JT Neal, E Shea, PI Thakore, L Jerby-Arnon, L Nguyen, D Dionne, ...
bioRxiv, 2020
22020
Methods and compositions for massively parallel variant and small molecule phenotyping
A Regev, P Thakore, J Doench, JT Neal, J Boehm, O Ursu
US Patent App. 16/809,458, 2020
12020
Using protein interaction networks to identify cancer dependencies from tumor genome data
H Horn, C Fagre, A Gupta, K Tsafou, N Fornelos, JT Neal, K Lage
bioRxiv, 2020
2020
Organoid-based characterization of patient tumors and microenvironments at single cell resolution
AA Salahudeen, J Zhu, J Ju, A Batish, K Sutha, JT Neal, V Giangarra, ...
Cancer Research 78 (13 Supplement), 987-987, 2018
2018
Methods to preserve tumor-stromal interactions in culture and therapeutic predictive applications thereof
J Neal, CJ Kuo
US Patent App. 15/793,249, 2018
2018
Patient-Derived Organoids as an In Vitro Model of Neuroendocrine Tumors
IH Liu, JT Neal, AJ Zemek, PL Kunz, CJ Kuo
PANCREAS 45 (3), 467-467, 2016
2016
Abstract LB-34: 3-Dimensional air-liquid interface organoid culture of primary human tumor biopsies
JT Neal, M Cantrell, P Rack, CJ Kuo
Cancer Research 74 (19 Supplement), LB-34-LB-34, 2014
2014
isease Models & Mechanisms DMM
JT Neal, TS Peterson, ML Kent, K Guillemin
2013
Bacterial Stimulation of Intestinal Proliferation via the Wnt Pathway in Zebrafish
JT Neal
University of Oregon, 2011
2011
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Articles 1–18