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J.T. Neal
J.T. Neal
Broad Institute of MIT and Harvard
Verified email at broadinstitute.org - Homepage
Title
Cited by
Cited by
Year
Organoid modeling of the tumor immune microenvironment
JT Neal, X Li, J Zhu, V Giangarra, CL Grzeskowiak, J Ju, IH Liu, SH Chiou, ...
Cell 175 (7), 1972-1988. e16, 2018
10412018
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis
J Rosenbluh, D Nijhawan, AG Cox, X Li, JT Neal, EJ Schafer, TI Zack, ...
Cell 151 (7), 1457-1473, 2012
8092012
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture
X Li, L Nadauld, A Ootani, DC Corney, RK Pai, O Gevaert, MA Cantrell, ...
Nature medicine 20 (7), 769-777, 2014
4232014
Epithelial cell proliferation in the developing zebrafish intestine is regulated by the Wnt pathway and microbial signaling via Myd88
SE Cheesman, JT Neal, E Mittge, BM Seredick, K Guillemin
Proceedings of the National Academy of Sciences 108 (supplement_1), 4570-4577, 2011
2672011
Massively parallel assessment of human variants with base editor screens
RE Hanna, M Hegde, CR Fagre, PC DeWeirdt, AK Sangree, Z Szegletes, ...
Cell 184 (4), 1064-1080. e20, 2021
2072021
H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model
JT Neal, TS Peterson, ML Kent, K Guillemin
Disease models & mechanisms 6 (3), 802-810, 2013
1262013
Surfactant Protein A2 (SP-A2) Variants Expressed in CHO Cells Stimulate Phagocytosis of Pseudomonas aeruginosa More than Do SP-A1 Variants
AN Mikerov, G Wang, TM Umstead, M Zacharatos, NJ Thomas, DS Phelps, ...
Infection and immunity 75 (3), 1403-1412, 2007
912007
Organoids as models for neoplastic transformation
JT Neal, CJ Kuo
Annual Review of Pathology: Mechanisms of Disease 11, 199-220, 2016
772016
Massively parallel phenotyping of coding variants in cancer with Perturb-seq
O Ursu, JT Neal, E Shea, PI Thakore, L Jerby-Arnon, L Nguyen, D Dionne, ...
Nature biotechnology 40 (6), 896-905, 2022
532022
Genome-wide analysis of somatic noncoding mutation patterns in cancer
F Dietlein, AB Wang, C Fagre, A Tang, NJM Besselink, E Cuppen, C Li, ...
Science 376 (6589), eabg5601, 2022
452022
The Purkinje cell degeneration 5J mutation is a single amino acid insertion that destabilizes Nna1 protein
L Chakrabarti, JT Neal, M Miles, RA Martinez, AC Smith, BL Sopher, ...
Mammalian genome 17, 103-110, 2006
422006
An Atlas of Variant Effects to understand the genome at nucleotide resolution
DM Fowler, DJ Adams, AL Gloyn, WC Hahn, DS Marks, LA Muffley, ...
Genome Biology 24 (1), 147, 2023
262023
Identification of genetic modifiers of CagA-induced epithelial disruption in Drosophila
DW Reid, JB Muyskens, JT Neal, GW Gaddini, LY Cho, AM Wandler, ...
Frontiers in Cellular and Infection Microbiology 2, 24, 2012
182012
CHK1 protects oncogenic KRAS-expressing cells from DNA damage and is a target for pancreatic cancer treatment
JE Klomp, YS Lee, CM Goodwin, B Papke, JA Klomp, AM Waters, ...
Cell reports 37 (9), 2021
162021
Massively parallel phenotyping of variant impact in cancer with Perturb-seq reveals a shift in the spectrum of cell states induced by somatic mutations
O Ursu, JT Neal, E Shea, PI Thakore, L Jerby-Arnon, L Nguyen, D Dionne, ...
Biorxiv, 2020.11. 16.383307, 2020
142020
A genome-wide atlas of human cell morphology
M Ramezani, J Bauman, A Singh, E Weisbart, J Yong, M Lozada, GP Way, ...
bioRxiv, 2023
82023
Methods and compositions for massively parallel variant and small molecule phenotyping
A Regev, P Thakore, J Doench, JT Neal, J Boehm, O Ursu
US Patent App. 16/809,458, 2020
22020
Cancer Informatics in 2017: A New Beginning and a Bright Future
JL Warner, DA Patt
Yearbook of Medical Informatics 27 (01), 223-226, 2018
22018
Pseudo-labeling enhanced by privileged information and its application to in situ sequencing images
M Haghighi, MC Cruz, E Weisbart, BA Cimini, A Singh, J Bauman, ...
arXiv preprint arXiv:2306.15898, 2023
2023
Automated analysis of significant noncoding mutations in somatic whole cancer genomes
F Dietlein, AB Wang, C Fagre, A Tang, N Besselink, E Cuppen, C Li, ...
Cancer Research 82 (12_Supplement), 2170-2170, 2022
2022
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