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Anna-Lena Heins
Anna-Lena Heins
Technical University of Munich, Institute for Biochemical Engineering
Verified email at tum.de
Title
Cited by
Cited by
Year
Experimental methods and modeling techniques for description of cell population heterogeneity
RL Fernandes, M Nierychlo, L Lundin, AE Pedersen, PEP Tellez, A Dutta, ...
Biotechnology advances 29 (6), 575-599, 2011
1462011
Challenges in industrial fermentation technology research
LR Formenti, A Nørregaard, A Bolic, DQ Hernandez, T Hagemann, ...
Biotechnology journal 9 (6), 727-738, 2014
922014
Physiological heterogeneities in microbial populations and implications for physical stress tolerance
M Carlquist, RL Fernandes, S Helmark, AL Heins, L Lundin, SJ Sørensen, ...
Microbial cell factories 11, 1-13, 2012
882012
Population heterogeneity in microbial bioprocesses: origin, analysis, mechanisms, and future perspectives
AL Heins, D Weuster-Botz
Bioprocess and biosystems engineering 41, 889-916, 2018
762018
Experimental and in silico investigation of population heterogeneity in continuous Sachharomyces cerevisiae scale‐down fermentation in a two‐compartment setup
AL Heins, R Lencastre Fernandes, KV Gernaey, AE Lantz
Journal of Chemical Technology & Biotechnology 90 (2), 324-340, 2015
472015
Applying mechanistic models in bioprocess development
R Lencastre Fernandes, VK Bodla, M Carlquist, AL Heins, ...
Measurement, monitoring, modelling and control of bioprocesses, 137-166, 2012
382012
Quantitative flow cytometry to understand population heterogeneity in response to changes in substrate availability in Escherichia coli and Saccharomyces cerevisiae chemostats
AL Heins, T Johanson, S Han, L Lundin, M Carlquist, KV Gernaey, ...
Frontiers in bioengineering and biotechnology 7, 187, 2019
362019
Cell mass and cell cycle dynamics of an asynchronous budding yeast population: experimental observations, flow cytometry data analysis, and multi‐scale modeling
RL Fernandes, M Carlquist, L Lundin, AL Heins, A Dutta, SJ Sørensen, ...
Biotechnology and bioengineering 110 (3), 812-826, 2013
362013
Development and characterization of Escherichia coli triple reporter strains for investigation of population heterogeneity in bioprocesses
AL Heins, J Reyelt, M Schmidt, H Kranz, D Weuster-Botz
Microbial cell factories 19, 1-20, 2020
162020
Advances in automated real‐time flow cytometry for monitoring of bioreactor processes
AL Heins, MD Hoang, D Weuster‐Botz
Engineering in life sciences 22 (3-4), 260-278, 2022
142022
Untargeted GC‐MS Metabolomics Reveals Changes in the Metabolite Dynamics of Industrial Scale Batch Fermentations of Streptoccoccus thermophilus Broth
B Khakimov, LD Christiansen, AL Heins, KM Sørensen, C Schöller, ...
Biotechnology journal 12 (10), 1700400, 2017
132017
The effect of acetate on population heterogeneity in different cellular characteristics of Escherichia coli in aerobic batch cultures
AL Heins, L Lundin, I Nunes, KV Gernaey, SJ Sørensen, AE Lantz
Biotechnology Progress 35 (3), e2796, 2019
72019
Application of an Escherichia coli triple reporter strain for at‐line monitoring of single‐cell physiology during L‐phenylalanine production
MD Hoang, DT Doan, M Schmidt, H Kranz, A Kremling, AL Heins
Engineering in life sciences 23 (1), e2100162, 2023
62023
Applications of coarse-grained models in metabolic engineering
DT Doan, MD Hoang, AL Heins, A Kremling
Frontiers in Molecular Biosciences 9, 806213, 2022
42022
Impact of mixing insufficiencies on L-phenylalanine production with an Escherichia coli reporter strain in a novel two-compartment bioreactor
MD Hoang, I Polte, L Frantzmann, N von den Eichen, AL Heins, ...
Microbial cell factories 22 (1), 153, 2023
12023
Influence of Varying Pre-Culture Conditions on the Level of Population Heterogeneity in Batch Cultures with an Escherichia coli Triple Reporter Strain
MD Hoang, S Riessner, JE Oropeza Vargas, N von den Eichen, AL Heins
Microorganisms 11 (7), 1763, 2023
12023
Population heterogeneity in Saccharomyces cerevisiae and Escherichia coli lab scale cultivations simulating industrial scale bioprocesses
AL Heins
Technical University of Denmark, 2014
12014
Dynamics in population heterogeneity during batch and continuous fermentation of Saccharomyces cerevisiae
AL Heins, R Lencastre Fernandes, L Lundin, M Carlquist, S Sörensen, ...
New Biotechnology 29, 1, 2012
12012
Versteckte Vielfalt: Diversität von Zellen im industriellen Bioprozess
P Arulrajah, AL Heins
BIOspektrum 29 (3), 241-244, 2023
2023
Hidden diversity: diversity of cells in industrial bioprocesses
P Arulrajah, AL Heins
BioSpektrum 29 (3), 241-244, 2023
2023
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