| Inhibition of SOAT1 suppresses glioblastoma growth via blocking SREBP-1–mediated lipogenesis F Geng, X Cheng, X Wu, JY Yoo, C Cheng, JY Guo, X Mo, P Ru, B Hurwitz, ... Clinical Cancer Research 22 (21), 5337-5348, 2016 | 255 | 2016 |
| Glucose-mediated N-glycosylation of SCAP is essential for SREBP-1 activation and tumor growth C Cheng, P Ru, F Geng, J Liu, JY Yoo, X Wu, X Cheng, V Euthine, P Hu, ... Cancer cell 28 (5), 569-581, 2015 | 237 | 2015 |
| Targeting DGAT1 ameliorates glioblastoma by increasing fat catabolism and oxidative stress X Cheng, F Geng, M Pan, X Wu, Y Zhong, C Wang, Z Tian, C Cheng, ... Cell metabolism 32 (2), 229-242. e8, 2020 | 179 | 2020 |
| Feedback loop regulation of SCAP/SREBP-1 by miR-29 modulates EGFR signaling-driven glioblastoma growth P Ru, P Hu, F Geng, X Mo, C Cheng, JY Yoo, X Cheng, X Wu, JY Guo, ... Cell reports 16 (6), 1527-1535, 2016 | 83 | 2016 |
| Lipid droplets maintain energy homeostasis and glioblastoma growth via autophagic release of stored fatty acids X Wu, F Geng, X Cheng, Q Guo, Y Zhong, TF Cloughesy, WH Yong, ... Iscience 23 (10), 2020 | 64 | 2020 |
| Nuclear IGF1R interacts with regulatory regions of chromatin to promote RNA polymerase II recruitment and gene expression associated with advanced tumor stage T Aleksic, N Gray, X Wu, G Rieunier, E Osher, J Mills, C Verrill, RJ Bryant, ... Cancer research 78 (13), 3497-3509, 2018 | 57 | 2018 |
| Bad to the bone: the role of the insulin-like growth factor axis in osseous metastasis G Rieunier, X Wu, VM Macaulay, AV Lee, U Weyer-Czernilofsky, ... Clinical Cancer Research 25 (12), 3479-3485, 2019 | 40 | 2019 |
| Increased EZH2 expression in prostate cancer is associated with metastatic recurrence following external beam radiotherapy X Wu, H Scott, SV Carlsson, DD Sjoberg, L Cerundolo, H Lilja, R Prevo, ... The Prostate 79 (10), 1079-1089, 2019 | 34 | 2019 |
| Analysis of SCAP N-glycosylation and Trafficking in Human Cells C Cheng, JY Guo, F Geng, X Wu, X Cheng, Q Li, D Guo JoVE (Journal of Visualized Experiments), e54709, 2016 | 15 | 2016 |
| Lipid droplets maintain energy homeostasis and glioblastoma growth via autophagic release of stored fatty acids. iScience 23 X Wu, F Geng, X Cheng, Q Guo, Y Zhong, TF Cloughesy, WH Yong, ... | 12 | 2020 |
| Targeting IGF perturbs global replication through ribonucleotide reductase dysfunction G Rieunier, X Wu, LE Harris, JV Mills, A Nandakumar, L Colling, E Seraia, ... Cancer research 81 (8), 2128-2141, 2021 | 10 | 2021 |
| CHK1 inhibition exacerbates replication stress induced by IGF blockade X Wu, E Seraia, SB Hatch, X Wan, DV Ebner, F Aroldi, Y Jiang, AJ Ryan, ... Oncogene 41 (4), 476-488, 2022 | 4 | 2022 |
| ReN VM spheroids in matrix: A neural progenitor three-dimensional in vitro model reveals DYRK1A inhibitors as potential regulators of radio-sensitivity X Wan, X Wu, MA Hill, DV Ebner Biochemical and Biophysical Research Communications 531 (4), 535-542, 2020 | 2 | 2020 |
| An improved in vivo angiogenesis model of chicken chorioallantoic membranes in surrogate shells revealed the pro-angiogenesis effects of chylomicrons X Wan, Z Zhang, L Rui, R Wilson, X Wu, X Liu Vascular Cell 11 (1), 2019 | 1 | 2019 |
| Cbio-07. Lipid droplets, A novel diagnostic biomarker and metabolic target in glioblastoma F Geng, X Cheng, X Wu, C Cheng, JY Guo, C Horbinski, B Kaur, ... Neuro-Oncology 18 (suppl_6), vi36-vi36, 2016 | 1 | 2016 |
| Exploiting replication stress induced by IGF blockade in cancer therapy X Wu University of Oxford, 2020 | | 2020 |
| Lipid droplets, a novel metabolic target in glioblastoma F Geng, J Guo, X Cheng, X Wu, C Cheng, A Chakravarti, D Guo Cancer Research 77 (13_Supplement), 3555-3555, 2017 | | 2017 |
| Erratum: Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth (Cell Reports (2016) 16 (6)(1527–1535)(S2211124716309032)(10 … P Ru, P Hu, F Geng, X Mo, C Cheng, JY Yoo, X Cheng, X Wu, JY Guo, ... Cell Reports 18 (4), 1076-1077, 2017 | | 2017 |
| SCAP links glucose to lipids for tumor growth C Cheng, F Geng, JY Guo, X Wu, X Cheng, A Chakravarti, D Guo Cancer Research 76 (14_Supplement), 25-25, 2016 | | 2016 |
| CSIG-04 Lipid metabolism reprogramming in glioblastoma and serving as promising target D Guo, C Cheng, F Geng, P Ru, X Wu, P Hu, X Cheng, B Kaur, ... Neuro-oncology 17 (suppl_5), v66-v66, 2015 | | 2015 |
