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Hansruedi Mathys
Hansruedi Mathys
Verified email at pitt.edu
Title
Cited by
Cited by
Year
Single-cell transcriptomic analysis of Alzheimer’s disease
H Mathys, J Davila-Velderrain, Z Peng, F Gao, S Mohammadi, JZ Young, ...
Nature 570 (7761), 332-337, 2019
16412019
Gamma frequency entrainment attenuates amyloid load and modifies microglia
HF Iaccarino, AC Singer, AJ Martorell, A Rudenko, F Gao, TZ Gillingham, ...
Nature 540 (7632), 230-235, 2016
10132016
Temporal tracking of microglia activation in neurodegeneration at single-cell resolution
H Mathys, C Adaikkan, F Gao, JZ Young, E Manet, M Hemberg, ...
Cell reports 21 (2), 366-380, 2017
5842017
Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer’s disease
E Gjoneska, AR Pfenning, H Mathys, G Quon, A Kundaje, LH Tsai, ...
Nature 518 (7539), 365-369, 2015
5702015
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation
MR Fabian, G Mathonnet, T Sundermeier, H Mathys, JT Zipprich, ...
Molecular cell 35 (6), 868-880, 2009
5212009
miRNA repression involves GW182-mediated recruitment of CCR4–NOT through conserved W-containing motifs
M Chekulaeva, H Mathys, JT Zipprich, J Attig, M Colic, R Parker, ...
Nature structural & molecular biology 18 (11), 1218-1226, 2011
4122011
Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression
H Mathys, J Basquin, S Ozgur, M Czarnocki-Cieciura, F Bonneau, ...
Molecular cell 54 (5), 751-765, 2014
3502014
Posttranscriptional gene regulation by spatial rearrangement of the 3′ untranslated region
AB Eberle, L Stalder, H Mathys, RZ Orozco, O Mühlemann
PLoS biology 6 (4), e92, 2008
3122008
Gamma entrainment binds higher-order brain regions and offers neuroprotection
C Adaikkan, SJ Middleton, A Marco, PC Pao, H Mathys, DNW Kim, F Gao, ...
Neuron 102 (5), 929-943. e8, 2019
2762019
Reconstruction of the human blood–brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes
JW Blanchard, M Bula, J Davila-Velderrain, LA Akay, L Zhu, A Frank, ...
Nature medicine 26 (6), 952-963, 2020
1892020
Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression
JT Zipprich, S Bhattacharyya, H Mathys, W Filipowicz
Rna 15 (5), 781-793, 2009
1892009
APOE4 impairs myelination via cholesterol dysregulation in oligodendrocytes
JW Blanchard, LA Akay, J Davila-Velderrain, D von Maydell, H Mathys, ...
Nature 611 (7937), 769-779, 2022
1312022
Single-cell dissection of the human brain vasculature
FJ Garcia, N Sun, H Lee, B Godlewski, H Mathys, K Galani, B Zhou, ...
Nature 603 (7903), 893-899, 2022
1312022
Noninvasive 40-Hz light flicker to recruit microglia and reduce amyloid beta load
AC Singer, AJ Martorell, JM Douglas, F Abdurrob, MK Attokaren, J Tipton, ...
Nature protocols 13 (8), 1850-1868, 2018
772018
AD-linked R47H-TREM2 mutation induces disease-enhancing microglial states via AKT hyperactivation
FA Sayed, L Kodama, L Fan, GK Carling, JC Udeochu, D Le, Q Li, L Zhou, ...
Science translational medicine 13 (622), eabe3947, 2021
542021
Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer’s disease pathology
H Mathys, Z Peng, CA Boix, MB Victor, N Leary, S Babu, G Abdelhady, ...
Cell 186 (20), 4365-4385. e27, 2023
362023
Human microglial state dynamics in Alzheimer’s disease progression
N Sun, MB Victor, YP Park, X Xiong, AN Scannail, N Leary, S Prosper, ...
Cell 186 (20), 4386-4403. e29, 2023
262023
A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes
G Colombo, RJA Cubero, L Kanari, A Venturino, R Schulz, M Scolamiero, ...
Nature Neuroscience 25 (10), 1379-1393, 2022
242022
Single-nucleus multiregion transcriptomic analysis of brain vasculature in Alzheimer’s disease
N Sun, LA Akay, MH Murdock, Y Park, F Galiana-Melendez, A Bubnys, ...
Nature Neuroscience, 1-13, 2023
192023
Epigenomic dissection of Alzheimer’s disease pinpoints causal variants and reveals epigenome erosion
X Xiong, BT James, CA Boix, YP Park, K Galani, MB Victor, N Sun, L Hou, ...
Cell 186 (20), 4422-4437. e21, 2023
172023
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