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Margaret Lange-Osborn
Margaret Lange-Osborn
Assistant Professor, Department of Molecular Microbiology & Immunology, Bond Life Sciences Center
Verified email at missouri.edu
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Cited by
Cited by
Year
Human endometrial epithelial cells cyclically express Toll-like receptor 3 (TLR3) and exhibit TLR3-dependent responses to dsRNA
RL Jorgenson, SL Young, MJ Lesmeister, TD Lyddon, ML Misfeldt
Human immunology 66 (5), 469-482, 2005
722005
High-throughput sequence analysis reveals structural diversity and improved potency among RNA inhibitors of HIV reverse transcriptase
MA Ditzler, MJ Lange, D Bose, CA Bottoms, KF Virkler, AW Sawyer, ...
Nucleic acids research 41 (3), 1873-1884, 2013
692013
Toll-like receptors in tonsillar epithelial cells
MJ Lange, JC Lasiter, ML Misfeldt
International journal of pediatric otorhinolaryngology 73 (4), 613-621, 2009
692009
17Beta-estradiol suppresses TLR3-induced cytokine and chemokine production in endometrial epithelial cells
MJ Lesmeister, RL Jorgenson, SL Young, ML Misfeldt
Reproductive Biology and Endocrinology 3, 1-15, 2005
602005
GS-CA compounds: first-in-class HIV-1 capsid inhibitors covering multiple grounds
K Singh, F Gallazzi, KJ Hill, DH Burke, MJ Lange, TP Quinn, U Neogi, ...
Frontiers in microbiology 10, 455764, 2019
582019
Modular cell-internalizing aptamer nanostructure enables targeted delivery of large functional RNAs in cancer cell lines
D Porciani, LN Cardwell, KD Tawiah, KK Alam, MJ Lange, MA Daniels, ...
Nature communications 9 (1), 2283, 2018
582018
Toll-like receptor expression in the human nasopharyngeal tonsil (adenoid) and palantine tonsils: a preliminary report
MJ Lesmeister, MR Bothwell, ML Misfeldt
International journal of pediatric otorhinolaryngology 70 (6), 987-992, 2006
502006
Robust suppression of HIV replication by intracellularly expressed reverse transcriptase aptamers is independent of ribozyme processing
MJ Lange, TK Sharma, AS Whatley, LA Landon, MA Tempesta, ...
Molecular Therapy 20 (12), 2304-2314, 2012
382012
Potent inhibition of HIV-1 reverse transcriptase and replication by nonpseudoknot,“UCAA-motif” RNA aptamers
AS Whatley, MA Ditzler, MJ Lange, E Biondi, AW Sawyer, JL Chang, ...
Molecular Therapy-Nucleic Acids 2, 2013
362013
RNA–protein interactions govern antiviral specificity and encapsidation of broad spectrum anti-HIV reverse transcriptase aptamers
MJ Lange, PDM Nguyen, MK Callaway, MC Johnson, DH Burke
Nucleic acids research 45 (10), 6087-6097, 2017
292017
Binding interface and impact on protease cleavage for an RNA aptamer to HIV-1 reverse transcriptase
PDM Nguyen, J Zheng, TJ Gremminger, L Qiu, D Zhang, S Tuske, ...
Nucleic acids research 48 (5), 2709-2722, 2020
242020
Poly-Target Selection Identifies Broad-Spectrum RNA Aptamers
DHB Khalid K. Alam, Jonathan L. Chang, Margaret J.Lange, Phuong D.M.Nguyen ...
Molecular Therapy Nucleic Acids 13, 605-619, 2018
192018
Activation of innate immune responses by a CpG oligonucleotide sequence composed entirely of threose nucleic acid
MJ Lange, DH Burke, JC Chaput
nucleic acid therapeutics 29 (1), 51-59, 2019
162019
The three-way junction structure of the HIV-1 PBS-segment binds host enzyme important for viral infectivity
Z Song, T Gremminger, G Singh, Y Cheng, J Li, L Qiu, J Ji, MJ Lange, ...
Nucleic acids research 49 (10), 5925-5942, 2021
132021
Diphtheria toxin A-resistant cell lines enable robust production and evaluation of DTA-encoding lentiviruses
MJ Lange, TD Lyddon, MC Johnson
Scientific reports 9 (1), 8985, 2019
132019
Selection and identification of an RNA aptamer that specifically binds the HIV-1 capsid lattice and inhibits viral replication
PR Gruenke, R Aneja, S Welbourn, OB Ukah, SG Sarafianos, DH Burke, ...
Nucleic Acids Research 50 (3), 1701-1717, 2022
122022
Screening inhibitory potential of anti-HIV RT RNA aptamers
MJ Lange, DH Burke
Therapeutic Applications of Ribozymes and Riboswitches: Methods and …, 2014
102014
Fourth report on chicken genes and chromosomes 2022
J Smith, JM Alfieri, N Anthony, P Arensburger, GN Athrey, J Balacco, ...
Cytogenetic and Genome Research 162 (8-9), 405-528, 2023
92023
Human endometrial TLR3 expression is cycle-dependent and localized to the epithelium.
SL Young, MJ Lesmeister, TD Lyddon, RL Jorgenson, ML Misfeldt
JOURNAL OF THE SOCIETY FOR GYNECOLOGIC INVESTIGATION 11 (2), 320A-320A, 2004
62004
Lipidated poly (amino acid) nanostructures as versatile therapeutic delivery vehicles
JD Smith, LN Cardwell, D Porciani, AJ Greenwald, AC Ellis, MC Schulte, ...
bioRxiv, 2020.04. 07.004333, 2020
42020
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