Functional selectivity of dopamine receptor agonists. I. Selective activation of postsynaptic dopamine D2 receptors linked to adenylate cyclase DM Mottola, JD Kilts, MM Lewis, HS Connery, QD Walker, SR Jones, ... Journal of Pharmacology and Experimental Therapeutics 301 (3), 1166-1178, 2002 | 160 | 2002 |
Domain swapping in the human histamine H1 receptor RA Bakker, G Dees, JJ Carrillo, RG Booth, JF López-Gimenez, G Milligan, ... Journal of Pharmacology and Experimental Therapeutics 311 (1), 131-138, 2004 | 95 | 2004 |
Effects of polychlorinated biphenyls (PCBs) on brain tyrosine hydroxylase activity and dopamine synthesis in rats NY Choksi, PRS Kodavanti, HA Tilson, RG Booth Fundamental and Applied Toxicology 39 (1), 76-80, 1997 | 82 | 1997 |
(+)-6, 7-Benzomorphan sigma ligands stimulate dopamine synthesis in rat corpus striatum tissue RG Booth, RJ Baldessarini Brain research 557 (1-2), 349-352, 1991 | 80 | 1991 |
Conformational Analysis, Pharmacophore Identification, and Comparative Molecular Field Analysis of Ligands for the Neuromodulatory. sigma. 3 Receptor AM Myers, PS Charifson, CE Owens, NS Kula, AT McPhail, ... Journal of medicinal chemistry 37 (24), 4109-4117, 1994 | 71 | 1994 |
Selective inhibition of Leishmania dihydrofolate reductase and Leishmania growth by 5-benzyl-2, 4-diaminopyrimidines W Sirawaraporn, R Sertsrivanich, RG Booth, C Hansch, RA Neal, ... Molecular and biochemical parasitology 31 (1), 79-85, 1988 | 68 | 1988 |
Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2, 5-dimethoxy-4-iodoamphetamine elicited … CE Canal, RG Booth, D Morgan Neuropharmacology 70, 112-121, 2013 | 59 | 2013 |
Novel ligands for the human histamine H1 receptor: synthesis, pharmacology, and comparative molecular field analysis studies of 2-dimethylamino-5-(6)-phenyl-1, 2, 3, 4 … OM Ghoneim, JA Legere, A Golbraikh, A Tropsha, RG Booth Bioorganic & medicinal chemistry 14 (19), 6640-6658, 2006 | 57 | 2006 |
Synthesis and pharmacological evaluation of 1-phenyl-3-amino-1, 2, 3, 4-tetrahydronaphthalenes as ligands for a novel receptor with. sigma.-like neuromodulatory activity SD Wyrick, RG Booth, AM Myers, CE Owens, NS Kula, RJ Baldessarini, ... Journal of medicinal chemistry 36 (17), 2542-2551, 1993 | 57 | 1993 |
New sigma-like receptor recognized by novel phenylaminotetralins: ligand binding and functional studies. RG Booth, SD Wyrick, RJ Baldessarini, NS Kula, AM Myers, RB Mailman Molecular pharmacology 44 (6), 1232-1239, 1993 | 55 | 1993 |
Intracerebral microdialysis neurotoxicity studies of quinoline and isoquinoline derivatives related to MPTP/MPP+ RG Booth, N Castagnoli Jr, H Rollema Neuroscience letters 100 (1-3), 306-312, 1989 | 54 | 1989 |
Inhibition of NADH oxidation by pyridine derivatives RR Ramsay, KA McKeown, EA Johnson, RG Booth, TP Singer Biochemical and biophysical research communications 146 (1), 53-60, 1987 | 54 | 1987 |
Synthesis, Evaluation, and Comparative Molecular Field Analysis of 1-Phenyl-3-amino-1,2,3,4-tetrahydronaphthalenes as Ligands for Histamine H1 Receptors EC Bucholtz, RL Brown, A Tropsha, RG Booth, SD Wyrick Journal of medicinal chemistry 42 (16), 3041-3054, 1999 | 53 | 1999 |
(1R, 3S)-(−)-Trans-PAT: A novel full-efficacy serotonin 5-HT2C receptor agonist with 5-HT2A and 5-HT2B receptor inverse agonist/antagonist activity RG Booth, L Fang, Y Huang, A Wilczynski, S Sivendran European journal of pharmacology 615 (1-3), 1-9, 2009 | 52 | 2009 |
GPCR Proteomics: Mass Spectrometric and Functional Analysis of Histamine H1 Receptor after Baculovirus-Driven and in Vitro Cell Free Expression K Sansuk, CIA Balog, AM van der Does, R Booth, WJ de Grip, AM Deelder, ... Journal of proteome research 7 (2), 621-629, 2008 | 52 | 2008 |
In vivo dopaminergic neurotoxicity of the 2-β-methylcarbolinium ion, a potential endogenous MPP+ analog H Rollema, RG Booth, N Castagnoli Jr European journal of pharmacology 153 (1), 131-134, 1988 | 52 | 1988 |
Ligand-directed functional heterogeneity of histamine H1 receptors: novel dual-function ligands selectively activate and block H1-mediated phospholipase C and adenylyl cyclase … NH Moniri, D Covington-Strachan, RG Booth Journal of Pharmacology and Experimental Therapeutics 311 (1), 274-281, 2004 | 49 | 2004 |
Quantitative structure-activity relationship of triazine-antifolate inhibition of Leishmania dihydrofolate reductase and cell growth RG Booth, CD Selassie, C Hansch, DV Santi Journal of medicinal chemistry 30 (7), 1218-1224, 1987 | 46 | 1987 |
Dopamine D1 autoreceptor function: possible expression in developing rat prefrontal cortex and striatum MH Teicher, AL Gallitano, HA Gelbard, HK Evans, ER Marsh, RG Booth, ... Developmental brain research 63 (1-2), 229-235, 1991 | 42 | 1991 |
In vivo intracerebral microdialysis studies in rats of MPP+ (1-methyl-4-phenylpyridinium) analogs and related charged species H Rollema, EA Johnson, RG Booth, P Caldera, P Lampen, SK Youngster, ... Journal of medicinal chemistry 33 (8), 2221-2230, 1990 | 42 | 1990 |