A bright future for precision medicine: advances in fluorescent chemical probe design and their clinical application M Garland, JJ Yim, M Bogyo Cell chemical biology 23 (1), 122-136, 2016 | 259 | 2016 |
Comparative Metabolomics Reveals Biogenesis of Ascarosides, a Modular Library of Small-Molecule Signals in C. elegans SH Von Reuss, N Bose, J Srinivasan, JJ Yim, JC Judkins, PW Sternberg, ... Journal of the American Chemical Society 134 (3), 1817-1824, 2012 | 235 | 2012 |
PD-1 inhibitory receptor downregulates asparaginyl endopeptidase and maintains Foxp3 transcription factor stability in induced regulatory T cells C Stathopoulou, A Gangaplara, G Mallett, FA Flomerfelt, LP Liniany, ... Immunity 49 (2), 247-263. e7, 2018 | 131 | 2018 |
Complex small-molecule architectures regulate phenotypic plasticity in a nematode N Bose, A Ogawa, SH von Reuss, JJ Yim, EJ Ragsdale, RJ Sommer, ... Angewandte Chemie (International ed. in English) 51 (50), 12438, 2012 | 119 | 2012 |
Transcranial magnetic stimulation in ALS: utility of central motor conduction tests AG Floyd, QP Yu, P Piboolnurak, MX Tang, Y Fang, WA Smith, J Yim, ... Neurology 72 (6), 498-504, 2009 | 94 | 2009 |
AND-gate contrast agents for enhanced fluorescence-guided surgery JC Widen, M Tholen, JJ Yim, A Antaris, KM Casey, S Rogalla, A Klaassen, ... Nature biomedical engineering 5 (3), 264-277, 2021 | 93 | 2021 |
Succinylated octopamine ascarosides and a new pathway of biogenic amine metabolism in Caenorhabditis elegans AB Artyukhin, JJ Yim, J Srinivasan, Y Izrayelit, N Bose, SH Von Reuss, ... Journal of Biological Chemistry 288 (26), 18778-18783, 2013 | 88 | 2013 |
Sex-specific mating pheromones in the nematode Panagrellus redivivus A Choe, T Chuman, SH von Reuss, AT Dossey, JJ Yim, R Ajredini, ... Proceedings of the National Academy of Sciences 109 (51), 20949-20954, 2012 | 79 | 2012 |
Natural variation in dauer pheromone production and sensing supports intraspecific competition in nematodes N Bose, JM Meyer, JJ Yim, MG Mayer, GV Markov, A Ogawa, ... Current Biology 24 (13), 1536-1541, 2014 | 61 | 2014 |
Optimization of a protease activated probe for optical surgical navigation JJ Yim, M Tholen, A Klaassen, J Sorger, M Bogyo Molecular Pharmaceutics 15 (3), 750-758, 2017 | 56 | 2017 |
Starvation-induced collective behavior in C. elegans AB Artyukhin, JJ Yim, M Cheong Cheong, L Avery Scientific reports 5 (1), 10647, 2015 | 54 | 2015 |
A protease-activated, near-infrared fluorescent probe for early endoscopic detection of premalignant gastrointestinal lesions JJ Yim, S Harmsen, K Flisikowski, T Flisikowska, H Namkoong, M Garland, ... Proceedings of the National Academy of Sciences 118 (1), e2008072118, 2021 | 51 | 2021 |
Linking genomic and metabolomic natural variation uncovers nematode pheromone biosynthesis JM Falcke, N Bose, AB Artyukhin, C Rödelsperger, GV Markov, JJ Yim, ... Cell chemical biology 25 (6), 787-796. e12, 2018 | 42 | 2018 |
B. subtilis GS67 protects C. elegans from Gram-positive pathogens via fengycin-mediated microbial antagonism I Iatsenko, JJ Yim, FC Schroeder, RJ Sommer Current Biology 24 (22), 2720-2727, 2014 | 39 | 2014 |
Synthesis of caeliferins, elicitors of plant immune responses: accessing lipophilic natural products via cross metathesis I O’Doherty, JJ Yim, EA Schmelz, FC Schroeder Organic Letters 13 (21), 5900-5903, 2011 | 34 | 2011 |
Fluorescent image-guided surgery in breast cancer by intravenous application of a quenched fluorescence activity-based probe for cysteine cathepsins in a syngeneic mouse model FV Suurs, SQ Qiu, JJ Yim, CP Schröder, H Timmer-Bosscha, ES Bensen, ... EJNMMI research 10, 1-10, 2020 | 32 | 2020 |
Design of Optical‐Imaging Probes by Screening of Diverse Substrate Libraries Directly in Disease‐Tissue Extracts M Tholen, JJ Yim, K Groborz, E Yoo, BA Martin, NS van den Berg, M Drag, ... Angewandte Chemie International Edition 59 (43), 19143-19152, 2020 | 21 | 2020 |
Nematode signaling molecules derived from multimodular assembly of primary metabolic building blocks JJ Yim, N Bose, JM Meyer, RJ Sommer, FC Schroeder Organic letters 17 (7), 1648-1651, 2015 | 21 | 2015 |
A protease-activated fluorescent probe allows rapid visualization of keratinocyte carcinoma during excision E Walker, Y Liu, IY Kim, M Biro, SR Iyer, H Ezaldein, J Scott, M Merati, ... Cancer research 80 (10), 2045-2055, 2020 | 19 | 2020 |
Synthetic and biological approaches to map substrate specificities of proteases S Chen, JJ Yim, M Bogyo Biological chemistry 401 (1), 165-182, 2019 | 19 | 2019 |