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Riikka Karjalainen
Riikka Karjalainen
Unknown affiliation
Verified email at helsinki.fi
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Year
Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia
T Pemovska, M Kontro, B Yadav, H Edgren, S Eldfors, A Szwajda, ...
Cancer discovery 3 (12), 1416-1429, 2013
4482013
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies
B Yadav, T Pemovska, A Szwajda, E Kulesskiy, M Kontro, R Karjalainen, ...
Scientific reports 4 (1), 1-10, 2014
3202014
JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell–induced protection of AML
R Karjalainen, T Pemovska, M Popa, M Liu, KK Javarappa, MM Majumder, ...
Blood, The Journal of the American Society of Hematology 130 (6), 789-802, 2017
1232017
Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia. Cancer Discov. 2013; 3: 1416–1429. doi: 10.1158/2159-8290
T Pemovska, M Kontro, B Yadav, H Edgren, S Eldfors, A Szwajda, ...
CD-13-0350.[Abstract][CrossRef][Google Scholar], 0
56
Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML
D Malani, A Murumägi, B Yadav, M Kontro, S Eldfors, A Kumar, ...
Leukemia 31 (5), 1187-1195, 2017
542017
Female mice expressing constitutively active mutants of FSH receptor present with a phenotype of premature follicle depletion and estrogen excess
H Peltoketo, L Strauss, R Karjalainen, M Zhang, GW Stamp, DL Segaloff, ...
Endocrinology 151 (4), 1872-1883, 2010
502010
Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary
F Naillat, W Yan, R Karjalainen, A Liakhovitskaia, A Samoylenko, Q Xu, ...
Experimental cell research 332 (2), 163-178, 2015
472015
Identification of precision treatment strategies for relapsed/refractory multiple myeloma by functional drug sensitivity testing
MM Majumder, R Silvennoinen, P Anttila, D Tamborero, S Eldfors, ...
Oncotarget 8 (34), 56338, 2017
442017
Elevated expression of S100A8 and S100A9 correlates with resistance to the BCL-2 inhibitor venetoclax in AML
R Karjalainen, M Liu, A Kumar, L He, D Malani, A Parsons, M Kontro, ...
Leukemia 33 (10), 2548-2553, 2019
342019
Statistical detection of quantitative protein biomarkers provides insights into signaling networks deregulated in acute myeloid leukemia
LL Elo, R Karjalainen, T Öhman, P Hintsanen, TA Nyman, CA Heckman, ...
Proteomics 14 (21-22), 2443-2453, 2014
142014
High-Throughput Ex Vivo Drug Sensitivity and Resistance Testing (DSRT) Integrated with Deep Genomic and Molecular Profiling Reveal New Therapy Options …
CA Heckman, M Kontro, T Pemovska, S Eldfors, H Edgren, E Kulesskiy, ...
Blood, The Journal of the American Society of Hematology 120 (21), 288-288, 2012
32012
Genomic and transcriptomic data integration in chronic myelomonocytic leukemia reveals a novel fusion gene involving onco-miR-125b-2
MM Majumder, M Kontro, H Edgren, D Nicorici, A Parsons, R Karjalainen, ...
Cancer Research 72 (8_Supplement), 3175-3175, 2012
32012
Combined targeting of BET family proteins and BCL2 Is synergistic in acute myeloid leukemia cells overexpressing S100A8 and S100A9
R Karjalainen, M Liu, A Kumar, A Parsons, L He, DR Malani, M Kontro, ...
Blood 132, 2634, 2018
22018
Identification and clinical exploration of individualized targeted therapeutic approaches in acute myeloid leukemia patients by integrating drug response and deep molecular …
D Malani, A Kumar, B Yadav, M Kontro, S Potdar, S Eldfors, J Saarela, ...
Blood, The Journal of the American Society of Hematology 130 (Suppl_1), 854-854, 2017
22017
Female mice expressing constitutively active FSH receptor present with a phenotype of premature follicle depletion, premature aging and teratomas
H Peltoketo, L Strauss, R Karjalainen, M Zhang, G Stamp, D Segaloff, ...
Endocrine Abstracts 21, 2010
22010
September 2013. Individualized Systems Medicine (ISM) strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia. Cancer Discov
T Pemovska, M Kontro, B Yadav, H Edgren, S Eldfors, A Szwajda, ...
21
Converging molecular evolution in acute myeloid leukaemia
C Engen, M Hellesøy, TH Dowling, S Eldfors, B Ferrell, SE Gullaksen, ...
medRxiv, 2020.11. 03.20222885, 2020
12020
Targeting of JAK/STAT Signaling to Reverse Stroma-Induced Cytoprotection Against BCL2 Antagonist Venetoclax in Acute Myeloid Leukemia
R Karjalainen, M Popa, M Liu, M Kontro, MM Safont, A Parsons, K Porkka, ...
Blood 128 (22), 32, 2016
12016
Identification of precision treatment strategies for high risk multiple myeloma by ex vivo drug sensitivity testing
MM Majumder, R Silvennoinen, P Anttila, D Tamborero, S Eldfors, ...
Clinical Lymphoma, Myeloma and Leukemia 15, e286, 2015
12015
Stromal Cell Supported High-Throughput Drug Testing Of Primary Leukemia Cells For Comprehensive Assessment Of Sensitivity To Novel Therapies
R Karjalainen, T Pemovska, B Yadav, MM Majumder, M Kontro, K Porkka, ...
Blood 122 (21), 1668, 2013
12013
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