Real-time DNA sequencing from single polymerase molecules J Eid, A Fehr, J Gray, K Luong, J Lyle, G Otto, P Peluso, D Rank, ... Science 323 (5910), 133-138, 2009 | 4754 | 2009 |
E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis H Müller, AP Bracken, R Vernell, MC Moroni, F Christians, E Grassilli, ... Genes & development 15 (3), 267-285, 2001 | 946 | 2001 |
Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1 DP Harkin, JM Bean, D Miklos, YH Song, VB Truong, C Englert, ... Cell 97 (5), 575-586, 1999 | 738 | 1999 |
Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious disease TA Blauwkamp, S Thair, MJ Rosen, L Blair, MS Lindner, ID Vilfan, T Kawli, ... Nature microbiology 4 (4), 663-674, 2019 | 661 | 2019 |
Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling FC Christians, L Scapozza, A Crameri, G Folkers, WPC Stemmer Nature biotechnology 17 (3), 259-264, 1999 | 443 | 1999 |
Two slow-step polymerase enzyme systems and methods K Bjornson, H Lee, J Korlach, S Turner, A Bibillo, F Christians, R Emig, ... US Patent 8,133,672, 2012 | 236 | 2012 |
Methods for identifying biological samples F Christians, R Mei US Patent App. 11/231,278, 2006 | 231 | 2006 |
Polymerases for nucleotide analogue incorporation DK Hanzel, G Otto, P Peluso, T Pham, DR Rank, P Mitsis, F Christians, ... US Patent 8,921,086, 2014 | 206 | 2014 |
Single molecule loading methods and compositions J Eid, S Turner, R Dalal, B Flusberg, J Korlach, S Lin, A Fehr, F Christians, ... US Patent 8,906,831, 2014 | 187 | 2014 |
Probe selection for high-density oligonucleotide arrays R Mei, E Hubbell, S Bekiranov, M Mittmann, FC Christians, MM Shen, ... Proceedings of the National Academy of Sciences 100 (20), 11237-11242, 2003 | 167 | 2003 |
Molecular redundant sequencing F Christians, S Turner US Patent 7,901,889, 2011 | 166 | 2011 |
Generation of modified polymerases for improved accuracy in single molecule sequencing S Clark, A Bibillo, P Peluso, F Christians, M He, I Park, H Lee, K Bjornson, ... US Patent 8,257,954, 2012 | 160 | 2012 |
Immobilized nucleic acid complexes for sequence analysis K Bjornson, A Bibillo, F Christians, K Travers, R Emig US Patent 8,481,264, 2013 | 133 | 2013 |
Recombinant polymerases for improved single molecule sequencing R Emig, L Jia, S Kamtekar, E Miller, C Cutcliffe, W Lee US Patent 8,999,676, 2015 | 132 | 2015 |
Enzymes resistant to photodamage K Bjornson, S Clark, I Park, F Christians US Patent 9,127,259, 2015 | 128 | 2015 |
Inhibition of transcription and strand-specific DNA repair by α-amanitin in Chinese hamster ovary cells FC Christians, PC Hanawalt Mutation Research/DNA Repair 274 (2), 93-101, 1992 | 128 | 1992 |
Methods for screening polypeptides F Christians, K Cole US Patent App. 09/683,613, 2003 | 124 | 2003 |
Multiple mutations in human cancers LA Loeb, FC Christians Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 350 (1 …, 1996 | 115 | 1996 |
Nucleic acid sequence analysis K Bjornson, A Bibillo, F Christians, K Travers, R Emig, S Turner US Patent 8,921,046, 2014 | 114 | 2014 |
Generation of modified polymerases for improved accuracy in single molecule sequencing S Clark, A Bibillo, P Peluso, F Christians, M He, I Park, H Lee, K Bjornson, ... US Patent 8,420,366, 2013 | 113 | 2013 |