|A map of human genome variation from population-scale sequencing|
1000 Genomes Project Consortium
Nature 467 (7319), 1061, 2010
|Integrating common and rare genetic variation in diverse human populations|
DM Altshuler, RA Gibbs, L Peltonen, E Dermitzakis, SF Schaffner, F Yu, ...
Nature 467 (7311), 52, 2010
|Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis|
S Sawcer, G Hellenthal, M Pirinen, CC Spencer, NA Patsopoulos, ...
|Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis|
AH Beecham, NA Patsopoulos, DK Xifara, MF Davis, A Kemppinen, ...
Nature genetics 45 (11), 1353, 2013
|A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1|
Nature Genetics, 2010
|The genetic architecture of type 2 diabetes|
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ...
Nature 536 (7614), 41-47, 2016
|Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility|
DM Evans, CCA Spencer, JJ Pointon, Z Su, D Harvey, G Kochan, ...
Nature Genetics 43 (8), 761-767, 2011
|Demographic history and rare allele sharing among human populations|
S Gravel, BM Henn, RN Gutenkunst, AR Indap, GT Marth, AG Clark, F Yu, ...
Proceedings of the National Academy of Sciences 108 (29), 11983-11988, 2011
|Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease|
KM De Lange, L Moutsianas, JC Lee, CA Lamb, Y Luo, NA Kennedy, ...
Nature genetics 49 (2), 256-261, 2017
|Class II HLA interactions modulate genetic risk for multiple sclerosis|
L Moutsianas, L Jostins, AH Beecham, AT Dilthey, DK Xifara, M Ban, ...
Nature genetics 47 (10), 1107, 2015
|Genetic mechanisms of critical illness in Covid-19|
E Pairo-Castineira, S Clohisey, L Klaric, AD Bretherick, K Rawlik, D Pasko, ...
Nature 591 (7848), 92-98, 2021
|HLA* IMP—an integrated framework for imputing classical HLA alleles from SNP genotypes|
AT Dilthey, L Moutsianas, S Leslie, G McVean
Bioinformatics 27 (7), 968, 2011
|Multi-population classical HLA type imputation|
A Dilthey, S Leslie, L Moutsianas, J Shen, C Cox, MR Nelson, G McVean
PLoS Comput Biol 9 (2), e1002877, 2013
|The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease|
L Moutsianas, V Agarwala, C Fuchsberger, J Flannick, MA Rivas, ...
PLoS Genet 11 (4), e1005165, 2015
|Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes|
AR Majithia, J Flannick, P Shahinian, M Guo, MA Bray, P Fontanillas, ...
Proceedings of the National Academy of Sciences 111 (36), 13127-13132, 2014
|Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7|
Y Luo, KM de Lange, L Jostins, L Moutsianas, J Randall, NA Kennedy, ...
Nature genetics 49 (2), 186-192, 2017
|Genome-wide association study implicates HLA-C* 01: 02 as a risk factor at the major histocompatibility complex locus in schizophrenia|
Irish Schizophrenia Genomics Consortium, ...
Biological psychiatry 72 (8), 620-628, 2012
|Revisiting the thrifty gene hypothesis via 65 loci associated with susceptibility to type 2 diabetes|
Q Ayub, L Moutsianas, Y Chen, K Panoutsopoulou, V Colonna, L Pagani, ...
The American Journal of Human Genetics 94 (2), 176-185, 2014
|A rare functional cardioprotective APOC3 variant has risen in frequency in distinct population isolates|
I Tachmazidou, G Dedoussis, L Southam, AE Farmaki, GRS Ritchie, ...
Nature communications 4 (1), 1-6, 2013
|HLA-DQA1* 05 carriage associated with development of anti-drug antibodies to infliximab and adalimumab in patients with Crohn’s disease|
A Sazonovs, NA Kennedy, L Moutsianas, GA Heap, DL Rice, M Reppell, ...
Gastroenterology 158 (1), 189-199, 2020