| The ‘Digital Twin’to enable the vision of precision cardiology J Corral-Acero, F Margara, M Marciniak, C Rodero, F Loncaric, Y Feng, ... European heart journal 41 (48), 4556-4564, 2020 | 384 | 2020 |
| Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiology OJ Britton, A Bueno-Orovio, K Van Ammel, HR Lu, R Towart, DJ Gallacher, ... Proceedings of the National Academy of Sciences 110 (23), E2098-E2105, 2013 | 332 | 2013 |
| Chaste: a test-driven approach to software development for biological modelling J Pitt-Francis, P Pathmanathan, MO Bernabeu, R Bordas, J Cooper, ... Computer Physics Communications 180 (12), 2452-2471, 2009 | 300 | 2009 |
| Human in silico drug trials demonstrate higher accuracy than animal models in predicting clinical pro-arrhythmic cardiotoxicity E Passini, OJ Britton, HR Lu, J Rohrbacher, AN Hermans, DJ Gallacher, ... Frontiers in physiology 8, 668, 2017 | 246 | 2017 |
| Fractional diffusion models of cardiac electrical propagation: role of structural heterogeneity in dispersion of repolarization A Bueno-Orovio, D Kay, V Grau, B Rodriguez, K Burrage Journal of The Royal Society Interface 11 (97), 20140352, 2014 | 222 | 2014 |
| Computational techniques for ECG analysis and interpretation in light of their contribution to medical advances A Lyon, A Mincholé, JP Martínez, P Laguna, B Rodriguez Journal of The Royal Society Interface 15 (138), 20170821, 2018 | 210 | 2018 |
| Generation of histo-anatomically representative models of the individual heart: tools and application G Plank, RAB Burton, P Hales, M Bishop, T Mansoori, MO Bernabeu, ... Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2009 | 199 | 2009 |
| Variability in cardiac electrophysiology: using experimentally-calibrated populations of models to move beyond the single virtual physiological human paradigm A Muszkiewicz, OJ Britton, P Gemmell, E Passini, C Sánchez, X Zhou, ... Progress in biophysics and molecular biology 120 (1-3), 115-127, 2016 | 169 | 2016 |
| Differences between left and right ventricular chamber geometry affect cardiac vulnerability to electric shocks B Rodriguez, L Li, JC Eason, IR Efimov, NA Trayanova Circulation research 97 (2), 168-175, 2005 | 156 | 2005 |
| In silico trials: Verification, validation and uncertainty quantification of predictive models used in the regulatory evaluation of biomedical products M Viceconti, F Pappalardo, B Rodriguez, M Horner, J Bischoff, ... Methods 185, 120-127, 2021 | 153 | 2021 |
| Multiscale modelling of drug-induced effects on cardiac electrophysiological activity T Brennan, M Fink, B Rodriguez European Journal of Pharmaceutical Sciences 36 (1), 62-77, 2009 | 141 | 2009 |
| Modeling cardiac ischemia B Rodriguez, N Trayanova, D Noble Annals of the New York academy of sciences 1080 (1), 395-414, 2006 | 140 | 2006 |
| Development, calibration, and validation of a novel human ventricular myocyte model in health, disease, and drug block J Tomek, A Bueno-Orovio, E Passini, X Zhou, A Minchole, O Britton, ... Elife 8, e48890, 2019 | 138 | 2019 |
| Impact of ionic current variability on human ventricular cellular electrophysiology L Romero, E Pueyo, M Fink, B Rodríguez American Journal of Physiology-Heart and Circulatory Physiology 297 (4 …, 2009 | 138 | 2009 |
| δ‐cells and β‐cells are electrically coupled and regulate α‐cell activity via somatostatin LJB Briant, TM Reinbothe, I Spiliotis, C Miranda, B Rodriguez, P Rorsman The Journal of physiology 596 (2), 197-215, 2018 | 137 | 2018 |
| A multiscale investigation of repolarization variability and its role in cardiac arrhythmogenesis E Pueyo, A Corrias, L Virág, N Jost, T Szél, A Varró, N Szentandrássy, ... Biophysical journal 101 (12), 2892-2902, 2011 | 135 | 2011 |
| Computational assessment of drug‐induced effects on the electrocardiogram: from ion channel to body surface potentials N Zemzemi, MO Bernabeu, J Saiz, J Cooper, P Pathmanathan, ... British journal of pharmacology 168 (3), 718-733, 2013 | 123 | 2013 |
| Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy E Passini, A Mincholé, R Coppini, E Cerbai, B Rodriguez, S Severi, ... Journal of molecular and cellular cardiology 96, 72-81, 2016 | 120 | 2016 |
| Inter-subject variability in human atrial action potential in sinus rhythm versus chronic atrial fibrillation C Sánchez, A Bueno-Orovio, E Wettwer, S Loose, J Simon, U Ravens, ... PloS one 9 (8), e105897, 2014 | 117 | 2014 |
| Bridging experiments, models and simulations: an integrative approach to validation in computational cardiac electrophysiology A Carusi, K Burrage, B Rodríguez American Journal of Physiology-Heart and Circulatory Physiology 303 (2 …, 2012 | 117 | 2012 |
