Eva Sjøttem
Eva Sjøttem
Associate Professor in Molecular Biology at the University of Tromsø
Verified email at - Homepage
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p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
A Jain, T Lamark, E Sjøttem, KB Larsen, JA Awuh, A Øvervatn, ...
Journal of biological chemistry 285 (29), 22576-22591, 2010
FKBP8 recruits LC3A to mediate Parkin‐independent mitophagy
Z Bhujabal, ÅB Birgisdottir, E Sjøttem, HB Brenne, A Øvervatn, S Habisov, ...
EMBO reports 18 (6), 947-961, 2017
The promoter activity of long terminal repeats of the HERV-H family of human retrovirus-like elements is critically dependent on Sp1 family proteins interacting with a GC/GT …
E Sjøttem, S Anderssen, T Johansen
Journal of virology 70 (1), 188-198, 1996
Members of the autophagy class III phosphatidylinositol 3-kinase complex I interact with GABARAP and GABARAPL1 via LIR motifs
ÅB Birgisdottir, S Mouilleron, Z Bhujabal, M Wirth, E Sjøttem, G Evjen, ...
Autophagy 15 (8), 1333-1355, 2019
ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8
M Skytte Rasmussen, S Mouilleron, B Kumar Shrestha, M Wirth, R Lee, ...
Autophagy 13 (5), 834-853, 2017
CALCOCO 1 acts with VAMP‐associated proteins to mediate ER‐phagy
TM Nthiga, B Kumar Shrestha, E Sjøttem, JA Bruun, K Bowitz Larsen, ...
The EMBO Journal 39 (15), e103649, 2020
The nuclear factor SPBP contains different functional domains and stimulates the activity of various transcriptional activators
C Rekdal, E Sjøttem, T Johansen
Journal of Biological Chemistry 275 (51), 40288-40300, 2000
Structural and functional analyses of DNA bending induced by Sp1 family transcription factors
E Sjøttem, C Andersen, T Johansen
Journal of molecular biology 267 (3), 490-504, 1997
SPBP is a sulforaphane induced transcriptional coactivator of NRF2 regulating expression of the autophagy receptor p62/SQSTM1
SR Darvekar, J Elvenes, HB Brenne, T Johansen, E Sjøttem
PLoS One 9 (1), e85262, 2014
p62/Sequestosome-1, autophagy-related gene 8, and autophagy in Drosophila are regulated by nuclear factor erythroid 2-related factor 2 (NRF2), independent of transcription …
A Jain, TE Rusten, N Katheder, J Elvenes, JA Bruun, E Sjøttem, T Lamark, ...
Journal of Biological Chemistry 290 (24), 14945-14962, 2015
Comparative analyses of LTRs of the ERV-H family of primate-specific retrovirus-like elements isolated from marmoset, African green monkey, and man
S Anderssen, E Sjøttem, G Svineng, T Johansen
Virology 234 (1), 14-30, 1997
Identification of two independent nucleosome-binding domains in the transcriptional co-activator SPBP
S Darvekar, SS Johnsen, AB Eriksen, T Johansen, E Sjøttem
Biochemical Journal 442 (1), 65-75, 2012
TRIM50 regulates Beclin 1 proautophagic activity
C Fusco, B Mandriani, M Di Rienzo, L Micale, N Malerba, D Cocciadiferro, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1865 (6), 908-919, 2018
Pax6 represses androgen receptor-mediated transactivation by inhibiting recruitment of the coactivator SPBP
J Elvenes, EIS Thomassen, SS Johnsen, K Kaino, E Sjøttem, T Johansen
PLoS One 6 (9), e24659, 2011
The recent transfer of a homing endonuclease gene
P Haugen, OG Wikmark, A Vader, DH Coucheron, E Sjøttem, ...
Nucleic acids research 33 (8), 2734-2741, 2005
A phylogenetic study of SPBP and RAI1: evolutionary conservation of chromatin binding modules
S Darvekar, C Rekdal, T Johansen, E Sjøttem
PLoS One 8 (10), e78907, 2013
The ePHD protein SPBP interacts with TopBP1 and together they co-operate to stimulate Ets1-mediated transcription
E Sjøttem, C Rekdal, G Svineng, SS Johnsen, H Klenow, RD Uglehus, ...
Nucleic acids research 35 (19), 6648-6662, 2007
TRIM32, but not its muscular dystrophy-associated mutant, positively regulates and is targeted to autophagic degradation by p62/SQSTM1
KS Overå, J Garcia-Garcia, Z Bhujabal, A Jain, A Øvervatn, KB Larsen, ...
Journal of Cell Science 132 (23), jcs236596, 2019
Generation of a PAX6 knockout glioblastoma cell line with changes in cell cycle distribution and sensitivity to oxidative stress
B Hegge, E Sjøttem, I Mikkola
BMC cancer 18, 1-19, 2018
NIMA-related kinase 9–mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1
BK Shrestha, MS Rasmussen, YP Abudu, JA Bruun, KB Larsen, EA Alemu, ...
Journal of Biological Chemistry 295 (5), 1240-1260, 2020
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