Prasant Chandran
Prasant Chandran
Abbott Laboratories, AbbVie Inc.
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Cited by
Cited by
A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2, 2-dimethylpropyl)-2-(3, 4-dimethoxyphenyl) acetamide], a novel and selective P2X7 receptor antagonist, dose …
P Honore, D Donnelly-Roberts, MT Namovic, G Hsieh, CZ Zhu, JP Mikusa, ...
Journal of Pharmacology and Experimental Therapeutics 319 (3), 1376-1385, 2006
TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists
M Cui, P Honore, C Zhong, D Gauvin, J Mikusa, G Hernandez, ...
Journal of Neuroscience 26 (37), 9385-9393, 2006
Development of opioid tolerance with repeated transcutaneous electrical nerve stimulation administration
P Chandran, KA Sluka
Pain 102 (1-2), 195-201, 2003
Indol-3-ylcycloalkyl Ketones: Effects of N1 Substituted Indole Side Chain Variations on CB2 Cannabinoid Receptor Activity
JM Frost, MJ Dart, KR Tietje, TR Garrison, GK Grayson, AV Daza, ...
Journal of medicinal chemistry 53 (1), 295-315, 2010
Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia
P Honore, P Chandran, G Hernandez, DM Gauvin, JP Mikusa, C Zhong, ...
Pain 142 (1-2), 27-35, 2009
In vitro and in vivo characterization of A‐796260: a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models
BB Yao, GC Hsieh, JM Frost, Y Fan, TR Garrison, AV Daza, GK Grayson, ...
British journal of pharmacology 153 (2), 390-401, 2008
Pharmacological modulation of movement-evoked pain in a rat model of osteoarthritis
P Chandran, M Pai, EA Blomme, GC Hsieh, MW Decker, P Honore
European journal of pharmacology 613 (1-3), 39-45, 2009
Central and peripheral sites of action for CB2 receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats
GC Hsieh, M Pai, P Chandran, BA Hooker, CZ Zhu, AK Salyers, ...
British journal of pharmacology 162 (2), 428-440, 2011
Comparison of antinociceptive actions of standard analgesics in attenuating capsaicin and nerve-injury-induced mechanical hypersensitivity
SK Joshi, G Hernandez, JP Mikusa, CZ Zhu, C Zhong, A Salyers, ...
Neuroscience 143 (2), 587-596, 2006
The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1αβ knockout mice
P Honore, D Donnelly-Roberts, M Namovic, C Zhong, C Wade, ...
Behavioural brain research 204 (1), 77-81, 2009
H4 receptor antagonism exhibits anti-nociceptive effects in inflammatory and neuropathic pain models in rats
GC Hsieh, P Chandran, AK Salyers, M Pai, CZ Zhu, EJ Wensink, DG Witte, ...
Pharmacology Biochemistry and Behavior 95 (1), 41-50, 2010
Default-mode-like network activation in awake rodents
J Upadhyay, SJ Baker, P Chandran, L Miller, Y Lee, GJ Marek, U Sakoglu, ...
PloS one 6 (11), e27839, 2011
Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2, 2, 3, 3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4, 5-dimethyl-3H-thiazol-(2Z …
BB Yao, G Hsieh, AV Daza, Y Fan, GK Grayson, TR Garrison, ...
Journal of Pharmacology and Experimental Therapeutics 328 (1), 141-151, 2009
Indol-3-yl-tetramethylcyclopropyl Ketones: Effects of Indole Ring Substitution on CB2 Cannabinoid Receptor Activity
JM Frost, MJ Dart, KR Tietje, TR Garrison, GK Grayson, AV Daza, ...
Journal of medicinal chemistry 51 (6), 1904-1912, 2008
Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI
CL Chin, AE Tovcimak, VP Hradil, TR Seifert, PR Hollingsworth, ...
British journal of pharmacology 153 (2), 367-379, 2008
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), A New Histamine H4R Antagonist that Blocks Pain …
H Liu, RJ Altenbach, TL Carr, P Chandran, GC Hsieh, LGR Lewis, ...
Journal of medicinal chemistry 51 (22), 7094-7098, 2008
Potentiation of analgesic efficacy but not side effects: co-administration of an α4β2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in …
CZ Zhu, C Chin, NR Rustay, C Zhong, J Mikusa, P Chandran, A Salyers, ...
Biochemical pharmacology 82 (8), 967-976, 2011
Magnetic resonance imaging and histological evidence for the blockade of cuprizone-induced demyelination in C57BL/6 mice
P Chandran, J Upadhyay, S Markosyan, A Lisowski, W Buck, CL Chin, ...
Neuroscience 202, 446-453, 2012
Enhanced reduction in hyperalgesia by combined administration of clonidine and TENS
KA Sluka, P Chandran
Pain 100 (1-2), 183-190, 2002
TRPV1-related modulation of spinal neuronal activity and behavior in a rat model of osteoarthritic pain
KL Chu, P Chandran, SK Joshi, MF Jarvis, PR Kym, S McGaraughty
Brain research 1369, 158-166, 2011
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