| A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2, 2-dimethylpropyl)-2-(3, 4-dimethoxyphenyl) acetamide], a novel and selective P2X7 receptor antagonist, dose … P Honore, D Donnelly-Roberts, MT Namovic, G Hsieh, CZ Zhu, JP Mikusa, ... Journal of pharmacology and experimental therapeutics 319 (3), 1376-1385, 2006 | 470 | 2006 |
| TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists M Cui, P Honore, C Zhong, D Gauvin, J Mikusa, G Hernandez, ... Journal of Neuroscience 26 (37), 9385-9393, 2006 | 399 | 2006 |
| Development of opioid tolerance with repeated transcutaneous electrical nerve stimulation administration P Chandran, KA Sluka Pain 102 (1-2), 195-201, 2003 | 199 | 2003 |
| Indol-3-ylcycloalkyl Ketones: Effects of N1 Substituted Indole Side Chain Variations on CB2 Cannabinoid Receptor Activity JM Frost, MJ Dart, KR Tietje, TR Garrison, GK Grayson, AV Daza, ... Journal of medicinal chemistry 53 (1), 295-315, 2010 | 181 | 2010 |
| Repeated dosing of ABT-102, a potent and selective TRPV1 antagonist, enhances TRPV1-mediated analgesic activity in rodents, but attenuates antagonist-induced hyperthermia P Honore, P Chandran, G Hernandez, DM Gauvin, JP Mikusa, C Zhong, ... Pain 142 (1-2), 27-35, 2009 | 170 | 2009 |
| In vitro and in vivo characterization of A‐796260: a selective cannabinoid CB2 receptor agonist exhibiting analgesic activity in rodent pain models BB Yao, GC Hsieh, JM Frost, Y Fan, TR Garrison, AV Daza, GK Grayson, ... British journal of pharmacology 153 (2), 390-401, 2008 | 161 | 2008 |
| Central and peripheral sites of action for CB2 receptor mediated analgesic activity in chronic inflammatory and neuropathic pain models in rats GC Hsieh, M Pai, P Chandran, BA Hooker, CZ Zhu, AK Salyers, ... British journal of pharmacology 162 (2), 428-440, 2011 | 147 | 2011 |
| Comparison of antinociceptive actions of standard analgesics in attenuating capsaicin and nerve-injury-induced mechanical hypersensitivity SK Joshi, G Hernandez, JP Mikusa, CZ Zhu, C Zhong, A Salyers, ... Neuroscience 143 (2), 587-596, 2006 | 134 | 2006 |
| Pharmacological modulation of movement-evoked pain in a rat model of osteoarthritis P Chandran, M Pai, EA Blomme, GC Hsieh, MW Decker, P Honore European journal of pharmacology 613 (1-3), 39-45, 2009 | 133 | 2009 |
| The antihyperalgesic activity of a selective P2X7 receptor antagonist, A-839977, is lost in IL-1αβ knockout mice P Honore, D Donnelly-Roberts, M Namovic, C Zhong, C Wade, ... Behavioural brain research 204 (1), 77-81, 2009 | 130 | 2009 |
| H4 receptor antagonism exhibits anti-nociceptive effects in inflammatory and neuropathic pain models in rats GC Hsieh, P Chandran, AK Salyers, M Pai, CZ Zhu, EJ Wensink, DG Witte, ... Pharmacology Biochemistry and Behavior 95 (1), 41-50, 2010 | 116 | 2010 |
| Default-mode-like network activation in awake rodents J Upadhyay, SJ Baker, P Chandran, L Miller, Y Lee, GJ Marek, U Sakoglu, ... PloS one 6 (11), e27839, 2011 | 105 | 2011 |
| Indol-3-yl-tetramethylcyclopropyl Ketones: Effects of Indole Ring Substitution on CB2 Cannabinoid Receptor Activity JM Frost, MJ Dart, KR Tietje, TR Garrison, GK Grayson, AV Daza, ... Journal of medicinal chemistry 51 (6), 1904-1912, 2008 | 101 | 2008 |
| Characterization of a cannabinoid CB2 receptor-selective agonist, A-836339 [2, 2, 3, 3-tetramethyl-cyclopropanecarboxylic acid [3-(2-methoxy-ethyl)-4, 5-dimethyl-3H-thiazol-(2Z … BB Yao, G Hsieh, AV Daza, Y Fan, GK Grayson, TR Garrison, ... Journal of Pharmacology and Experimental Therapeutics 328 (1), 141-151, 2009 | 99 | 2009 |
| Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI CL Chin, AE Tovcimak, VP Hradil, TR Seifert, PR Hollingsworth, ... British journal of pharmacology 153 (2), 367-379, 2008 | 93 | 2008 |
| cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), A New Histamine H4R Antagonist that Blocks Pain … H Liu, RJ Altenbach, TL Carr, P Chandran, GC Hsieh, LGR Lewis, ... Journal of medicinal chemistry 51 (22), 7094-7098, 2008 | 69 | 2008 |
| Magnetic resonance imaging and histological evidence for the blockade of cuprizone-induced demyelination in C57BL/6 mice P Chandran, J Upadhyay, S Markosyan, A Lisowski, W Buck, CL Chin, ... Neuroscience 202, 446-453, 2012 | 62 | 2012 |
| Potentiation of analgesic efficacy but not side effects: co-administration of an α4β2 neuronal nicotinic acetylcholine receptor agonist and its positive allosteric modulator in … CZ Zhu, C Chin, NR Rustay, C Zhong, J Mikusa, P Chandran, A Salyers, ... Biochemical pharmacology 82 (8), 967-976, 2011 | 62 | 2011 |
| TRPV1-related modulation of spinal neuronal activity and behavior in a rat model of osteoarthritic pain KL Chu, P Chandran, SK Joshi, MF Jarvis, PR Kym, S McGaraughty Brain research 1369, 158-166, 2011 | 59 | 2011 |
| Enhanced reduction in hyperalgesia by combined administration of clonidine and TENS KA Sluka, P Chandran Pain 100 (1), 183-190, 2002 | 51 | 2002 |
