Cytotoxicity of thermosensitive polymers poly (N-isopropylacrylamide), poly (N-vinylcaprolactam) and amphiphilically modified poly (N-vinylcaprolactam) H Vihola, A Laukkanen, L Valtola, H Tenhu, J Hirvonen Biomaterials 26 (16), 3055-3064, 2005 | 633 | 2005 |
Mesoporous silicon microparticles for oral drug delivery: loading and release of five model drugs J Salonen, L Laitinen, AM Kaukonen, J Tuura, M Björkqvist, T Heikkilä, ... Journal of controlled release 108 (2-3), 362-374, 2005 | 561 | 2005 |
Mesoporous silicon in drug delivery applications J Salonen, AM Kaukonen, J Hirvonen, VP Lehto Journal of pharmaceutical sciences 97 (2), 632-653, 2008 | 491 | 2008 |
Biocompatibility of thermally hydrocarbonized porous silicon nanoparticles and their biodistribution in rats LM Bimbo, M Sarparanta, HA Santos, AJ Airaksinen, E Makila, ... ACS nano 4 (6), 3023-3032, 2010 | 313 | 2010 |
Pharmaceutical nanocrystals by nanomilling: critical process parameters, particle fracturing and stabilization methods L Peltonen, J Hirvonen Journal of pharmacy and pharmacology 62 (11), 1569-1579, 2010 | 291 | 2010 |
Mesoporous silica material TUD-1 as a drug delivery system T Heikkilä, J Salonen, J Tuura, MS Hamdy, G Mul, N Kumar, T Salmi, ... International journal of pharmaceutics 331 (1), 133-138, 2007 | 235 | 2007 |
Properties and chemical modifications of lignin: Towards lignin-based nanomaterials for biomedical applications P Figueiredo, K Lintinen, JT Hirvonen, MA Kostiainen, HA Santos Progress in Materials Science 93, 233-269, 2018 | 234 | 2018 |
Nanosuspensions of poorly soluble drugs: preparation and development by wet milling P Liu, X Rong, J Laru, B van Veen, J Kiesvaara, J Hirvonen, T Laaksonen, ... International journal of pharmaceutics 411 (1-2), 215-222, 2011 | 209 | 2011 |
Drug release from nanoparticles embedded in four different nanofibrillar cellulose aerogels H Valo, S Arola, P Laaksonen, M Torkkeli, L Peltonen, MB Linder, ... European Journal of Pharmaceutical Sciences 50 (1), 69-77, 2013 | 199 | 2013 |
Nanofibrillar cellulose films for controlled drug delivery R Kolakovic, L Peltonen, A Laukkanen, J Hirvonen, T Laaksonen European Journal of Pharmaceutics and Biopharmaceutics 82 (2), 308-315, 2012 | 193 | 2012 |
Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs): UGT1A9 is more resistant to detergent inhibition than the other UGTs and was purified … M Kurkela, JA Garcı́a-Horsman, L Luukkanen, S Mörsky, J Taskinen, ... Journal of Biological Chemistry 278 (6), 3536-3544, 2003 | 182 | 2003 |
Binding and release of drugs into and from thermosensitive poly (N-vinyl caprolactam) nanoparticles H Vihola, A Laukkanen, J Hirvonen, H Tenhu European Journal of Pharmaceutical Sciences 16 (1-2), 69-74, 2002 | 175 | 2002 |
Evaluation of mesoporous TCPSi, MCM-41, SBA-15, and TUD-1 materials as API carriers for oral drug delivery T Heikkilä, J Salonen, J Tuura, N Kumar, T Salmi, DY Murzin, MS Hamdy, ... Drug delivery 14 (6), 337-347, 2007 | 172 | 2007 |
In vitro cytotoxicity of porous silicon microparticles: effect of the particle concentration, surface chemistry and size HA Santos, J Riikonen, J Salonen, E Mäkilä, T Heikkilä, T Laaksonen, ... Acta biomaterialia 6 (7), 2721-2731, 2010 | 168 | 2010 |
Drug permeation across intestinal epithelial cells using porous silicon nanoparticles LM Bimbo, E Mäkilä, T Laaksonen, VP Lehto, J Salonen, J Hirvonen, ... Biomaterials 32 (10), 2625-2633, 2011 | 163 | 2011 |
The mechanisms of surface chemistry effects of mesoporous silicon nanoparticles on immunotoxicity and biocompatibility MA Shahbazi, M Hamidi, EM Mäkilä, H Zhang, PV Almeida, ... Biomaterials 34 (31), 7776-7789, 2013 | 157 | 2013 |
Failure of MTT as a toxicity testing agent for mesoporous silicon microparticles T Laaksonen, H Santos, H Vihola, J Salonen, J Riikonen, T Heikkilä, ... Chemical research in toxicology 20 (12), 1913-1918, 2007 | 157 | 2007 |
In vitro evaluation of biodegradable lignin-based nanoparticles for drug delivery and enhanced antiproliferation effect in cancer cells P Figueiredo, K Lintinen, A Kiriazis, V Hynninen, Z Liu, T Bauleth-Ramos, ... Biomaterials 121, 97-108, 2017 | 156 | 2017 |
Drug delivery formulations of ordered and nonordered mesoporous silica: comparison of three drug loading methods T Limnell, HA Santos, E Mäkilä, T Heikkilä, J Salonen, DY Murzin, ... Journal of pharmaceutical sciences 100 (8), 3294-3306, 2011 | 153 | 2011 |
Porous silicon nanoparticles for nanomedicine: preparation and biomedical applications HA Santos, E Mäkilä, AJ Airaksinen, LM Bimbo, J Hirvonen Nanomedicine 9 (4), 535-554, 2014 | 144 | 2014 |