| The Apaf-1 apoptosome: a large caspase-activating complex K Cain, SB Bratton, GM Cohen Biochimie 84 (2-3), 203-214, 2002 | 621 | 2002 |
| Regulation of the Apaf-1–caspase-9 apoptosome SB Bratton, GS Salvesen Journal of cell science 123 (19), 3209-3214, 2010 | 560 | 2010 |
| Protein complexes activate distinct caspase cascades in death receptor and stress-induced apoptosis SB Bratton, M MacFarlane, K Cain, GM Cohen Experimental cell research 256 (1), 27-33, 2000 | 554 | 2000 |
| Recruitment, activation and retention of caspases‐9 and‐3 by Apaf‐1 apoptosome and associated XIAP complexes SB Bratton, G Walker, SM Srinivasula, XM Sun, M Butterworth, ES Alnemri, ... The EMBO journal, 2001 | 545 | 2001 |
| Apaf-1 oligomerizes into biologically active∼ 700-kDa and inactive∼ 1.4-MDa apoptosome complexes K Cain, SB Bratton, C Langlais, G Walker, DG Brown, XM Sun, GM Cohen Journal of Biological Chemistry 275 (9), 6067-6070, 2000 | 530 | 2000 |
| Regulation of the intrinsic apoptosis pathway by reactive oxygen species CC Wu, SB Bratton Antioxidants & redox signaling 19 (6), 546-558, 2013 | 394 | 2013 |
| Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro M MacFarlane, W Merrison, SB Bratton, GM Cohen Journal of Biological Chemistry 277 (39), 36611-36616, 2002 | 390 | 2002 |
| Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein XM Sun, SB Bratton, M Butterworth, M MacFarlane, GM Cohen Journal of Biological Chemistry 277 (13), 11345-11351, 2002 | 282 | 2002 |
| Apoptotic death sensor: an organelle's alter ego? SB Bratton, GM Cohen Trends in Pharmacological Sciences 22 (6), 306-315, 2001 | 263 | 2001 |
| XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders AR Mufti, E Burstein, RA Csomos, PCF Graf, JC Wilkinson, RD Dick, ... Molecular cell 21 (6), 775-785, 2006 | 234 | 2006 |
| The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and-7 via unique mechanisms at distinct steps in their processing YE Choi, M Butterworth, S Malladi, CS Duckett, GM Cohen, SB Bratton Journal of Biological Chemistry 284 (19), 12772-12782, 2009 | 204 | 2009 |
| The Apaf‐1• procaspase‐9 apoptosome complex functions as a proteolytic‐based molecular timer S Malladi, M Challa‐Malladi, HO Fearnhead, SB Bratton The EMBO journal 28 (13), 1916-1925, 2009 | 173 | 2009 |
| XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95-and Bax-induced apoptosis SB Bratton, J Lewis, M Butterworth, CS Duckett, GM Cohen Cell Death & Differentiation 9 (9), 881-892, 2002 | 164 | 2002 |
| Uncoupling of the signaling and caspase-inhibitory properties of X-linked inhibitor of apoptosis J Lewis, E Burstein, SB Reffey, SB Bratton, AB Roberts, CS Duckett Journal of biological chemistry 279 (10), 9023-9029, 2004 | 148 | 2004 |
| Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptosome D Chandra, SB Bratton, MD Person, Y Tian, AG Martin, M Ayres, ... Cell 125 (7), 1333-1346, 2006 | 140 | 2006 |
| ‘Heated’debates in apoptosis RS Milleron, SB Bratton Cellular and Molecular Life Sciences 64, 2329-2333, 2007 | 98 | 2007 |
| Heat shock induces apoptosis independently of any known initiator caspase-activating complex RS Milleron, SB Bratton Journal of Biological Chemistry 281 (25), 16991-17000, 2006 | 82 | 2006 |
| The Apaf-1 apoptosome induces formation of caspase-9 homo-and heterodimers with distinct activities CC Wu, S Lee, S Malladi, MD Chen, NJ Mastrandrea, Z Zhang, SB Bratton Nature communications 7 (1), 13565, 2016 | 80 | 2016 |
| Quinone electrophiles selectively adduct “electrophile binding motifs” within cytochrome c AA Fisher, MT Labenski, S Malladi, V Gokhale, ME Bowen, RS Milleron, ... Biochemistry 46 (39), 11090-11100, 2007 | 73 | 2007 |
| Reciprocity in ROS and autophagic signaling DJ Wible, SB Bratton Current opinion in toxicology 7, 28-36, 2018 | 69 | 2018 |
