| Transition metal complexes as drugs and chemotherapeutic agents N Farrell Springer Science & Business Media, 2012 | 557 | 2012 |
| Activation of the trans geometry in platinum antitumor complexes. Synthesis, characterization, and biological activity of complexes with the planar ligands pyridine, N … M Van Beusichem, N Farrell Inorganic Chemistry 31 (4), 634-639, 1992 | 315 | 1992 |
| Biomedical uses and applications of inorganic chemistry. An overview N Farrell Coordination Chemistry Reviews 232 (1-2), 1-4, 2002 | 302 | 2002 |
| DNA modifications by a novel bifunctional trinuclear platinum phase I anticancer agent V Brabec, J Kašpárková, O Vrána, O Nováková, JW Cox, Y Qu, N Farrell Biochemistry 38 (21), 6781-6790, 1999 | 296 | 1999 |
| Activation of the trans Geometry in Platinum Antitumor Complexes: A Survey of the Cytotoxicity of trans Complexes Containing Planar Ligands in Murine L1210 … N Farrell, LR Kelland, JD Roberts, M Van Beusichem Cancer Research 52 (18), 5065-5072, 1992 | 292 | 1992 |
| BBR 3464: a novel triplatinum complex, exhibiting a preclinical profile of antitumor efficacy different from cisplatin C Manzotti, G Pratesi, E Menta, R Di Domenico, E Cavalletti, HH Fiebig, ... Clinical cancer research 6 (7), 2626-2634, 2000 | 263 | 2000 |
| A comparison of chemical reactivity, cytotoxicity, interstrand crosslinking and DNA sequence specificity of bis (platinum) complexes containing monodentate or bidentate … N Farrell, Y Qu, L Feng, B Van Houten Biochemistry 29 (41), 9522-9531, 1990 | 259 | 1990 |
| Cytostatic trans-platinum (II) complexes N Farrell, TTB Ha, JP Souchard, FL Wimmer, S Cros, NP Johnson Journal of medicinal chemistry 32 (10), 2240-2241, 1989 | 251 | 1989 |
| Molecular methods for assessment of non-covalent metallodrug–DNA interactions A Kellett, Z Molphy, C Slator, V McKee, NP Farrell Chemical Society Reviews 48 (4), 971-988, 2019 | 233 | 2019 |
| Cytotoxicity and antitumor activity of bis (platinum) complexes. A novel class of platinum complexes active in cell lines resistant to both cisplatin and 1, 2 … N Farrell, Y Qu, MP Hacker Journal of medicinal chemistry 33 (8), 2179-2184, 1990 | 222 | 1990 |
| A third mode of DNA binding: phosphate clamps by a polynuclear platinum complex S Komeda, T Moulaei, KK Woods, M Chikuma, NP Farrell, LD Williams Journal of the American Chemical Society 128 (50), 16092-16103, 2006 | 220 | 2006 |
| Polynuclear platinum drugs N Farrell Metal ions in biological systems 42, 251-296, 2004 | 215 | 2004 |
| PLATINUM-BASEDDRUGS INCANCER THERAPY LR Kelland, NP Farrell | 211 | 2000 |
| A novel trinuclear platinum complex overcomes cisplatin resistance in an osteosarcoma cell system P Perego, C Caserini, L Gatti, N Carenini, S Romanelli, R Supino, ... Molecular pharmacology 55 (3), 528-534, 1999 | 210 | 1999 |
| Current status of structure-activity relationships of platinum anticancer drugs: activation of the trans geometry N Farrell Metal ions in biological systems 32, 603-639, 1996 | 206 | 1996 |
| Metal complexes as drugs and chemotherapeutic agents N Farrell Pergamon, 2003 | 200* | 2003 |
| Transferring the concept of multinuclearity to ruthenium complexes for improvement of anticancer activity MG Mendoza-Ferri, CG Hartinger, MA Mendoza, M Groessl, AE Egger, ... Journal of medicinal chemistry 52 (4), 916-925, 2009 | 199 | 2009 |
| Zinc metalloproteins as medicinal targets AI Anzellotti, NP Farrell Chemical Society Reviews 37 (8), 1629-1651, 2008 | 199 | 2008 |
| Multi-platinum anti-cancer agents. Substitution-inert compounds for tumor selectivity and new targets NP Farrell Chemical Society Reviews 44 (24), 8773-8785, 2015 | 193 | 2015 |
| DNA interstrand cross-links of the novel antitumor trinuclear platinum complex BBR3464: conformation, recognition by high mobility group domain proteins, and nucleotide … J Kasparkova, J Zehnulova, N Farrell, V Brabec Journal of Biological Chemistry 277 (50), 48076-48086, 2002 | 191 | 2002 |
Erica J PetersonVirginia Commonwealth UniversityVerified email at vcu.edu
