Delivering nanomedicine to solid tumors RK Jain, T Stylianopoulos Nature reviews Clinical oncology 7 (11), 653, 2010 | 3571 | 2010 |
Normalization of tumour blood vessels improves the delivery of nanomedicines in a size-dependent manner VP Chauhan, T Stylianopoulos, JD Martin, Z Popović, O Chen, ... Nano-Enabled Medical Applications, 279-311, 2020 | 1167 | 2020 |
Multistage nanoparticle delivery system for deep penetration into tumor tissue C Wong, T Stylianopoulos, J Cui, J Martin, VP Chauhan, W Jiang, ... Proceedings of the National Academy of Sciences 108 (6), 2426-2431, 2011 | 1107 | 2011 |
The role of mechanical forces in tumor growth and therapy RK Jain, JD Martin, T Stylianopoulos Annual review of biomedical engineering 16 (1), 321-346, 2014 | 1058 | 2014 |
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels VP Chauhan, JD Martin, H Liu, DA Lacorre, SR Jain, SV Kozin, ... Nature communications 4 (1), 2516, 2013 | 972 | 2013 |
Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors T Stylianopoulos, JD Martin, VP Chauhan, SR Jain, B Diop-Frimpong, ... Proceedings of the National Academy of Sciences 109 (38), 15101-15108, 2012 | 889 | 2012 |
Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging BJ Vakoc, RM Lanning, JA Tyrrell, TP Padera, LA Bartlett, ... Nature medicine 15 (10), 1219-1223, 2009 | 833 | 2009 |
Delivery of molecular and nanoscale medicine to tumors: transport barriers and strategies VP Chauhan, T Stylianopoulos, Y Boucher, RK Jain Annual review of chemical and biomolecular engineering 2 (1), 281-298, 2011 | 659 | 2011 |
Improving cancer immunotherapy using nanomedicines: progress, opportunities and challenges JD Martin, H Cabral, T Stylianopoulos, RK Jain Nature reviews Clinical oncology 17 (4), 251-266, 2020 | 537 | 2020 |
Reengineering the physical microenvironment of tumors to improve drug delivery and efficacy: from mathematical modeling to bench to bedside T Stylianopoulos, LL Munn, RK Jain Trends in cancer 4 (4), 292-319, 2018 | 498 | 2018 |
Combining two strategies to improve perfusion and drug delivery in solid tumors T Stylianopoulos, RK Jain Proceedings of the National Academy of Sciences 110 (46), 18632-18637, 2013 | 496 | 2013 |
Coevolution of solid stress and interstitial fluid pressure in tumors during progression: implications for vascular collapse T Stylianopoulos, JD Martin, M Snuderl, F Mpekris, SR Jain, RK Jain Cancer research 73 (13), 3833-3841, 2013 | 473 | 2013 |
Diffusion of particles in the extracellular matrix: the effect of repulsive electrostatic interactions T Stylianopoulos, MZ Poh, N Insin, MG Bawendi, D Fukumura, LL Munn, ... Biophysical journal 99 (5), 1342-1349, 2010 | 461 | 2010 |
Cell adhesion and matrix stiffness: coordinating cancer cell invasion and metastasis V Gkretsi, T Stylianopoulos Frontiers in oncology 8, 145, 2018 | 413 | 2018 |
The role of tumor microenvironment in cancer metastasis: Molecular mechanisms and therapeutic opportunities CM Neophytou, M Panagi, T Stylianopoulos, P Papageorgis Cancers 13 (9), 2053, 2021 | 291 | 2021 |
Design considerations for nanotherapeutics in oncology T Stylianopoulos, RK Jain Nanomedicine: Nanotechnology, Biology and Medicine 11 (8), 1893-1907, 2015 | 286 | 2015 |
Defining the role of solid stress and matrix stiffness in cancer cell proliferation and metastasis M Kalli, T Stylianopoulos Frontiers in oncology 8, 55, 2018 | 267 | 2018 |
Volume-averaging theory for the study of the mechanics of collagen networks T Stylianopoulos, VH Barocas Computer methods in applied mechanics and engineering 196 (31-32), 2981-2990, 2007 | 256 | 2007 |
Role of TGFβ in regulation of the tumor microenvironment and drug delivery P Papageorgis, T Stylianopoulos International journal of oncology 46 (3), 933-943, 2015 | 226 | 2015 |
Losartan treatment enhances chemotherapy efficacy and reduces ascites in ovarian cancer models by normalizing the tumor stroma Y Zhao, J Cao, A Melamed, M Worley, A Gockley, D Jones, HT Nia, ... Proceedings of the National Academy of Sciences 116 (6), 2210-2219, 2019 | 219 | 2019 |