Combining an autologous peripheral nervous system “bridge” and matrix modification by chondroitinase allows robust, functional regeneration beyond a hemisection lesion of the … JD Houle, VJ Tom, D Mayes, G Wagoner, N Phillips, J Silver Journal of Neuroscience 26 (28), 7405-7415, 2006 | 380 | 2006 |
Studies on the development and behavior of the dystrophic growth cone, the hallmark of regeneration failure, in an in vitro model of the glial scar and after spinal cord injury VJ Tom, MP Steinmetz, JH Miller, CM Doller, J Silver Journal of Neuroscience 24 (29), 6531-6539, 2004 | 359 | 2004 |
Chronic enhancement of the intrinsic growth capacity of sensory neurons combined with the degradation of inhibitory proteoglycans allows functional regeneration of sensory … MP Steinmetz, KP Horn, VJ Tom, JH Miller, SA Busch, D Nair, DJ Silver, ... Journal of Neuroscience 25 (35), 8066-8076, 2005 | 236 | 2005 |
Astrocyte-associated fibronectin is critical for axonal regeneration in adult white matter VJ Tom, CM Doller, AT Malouf, J Silver Journal of Neuroscience 24 (42), 9282-9290, 2004 | 227 | 2004 |
Combining peripheral nerve grafts and chondroitinase promotes functional axonal regeneration in the chronically injured spinal cord VJ Tom, HR Sandrow-Feinberg, K Miller, L Santi, T Connors, MA Lemay, ... Journal of Neuroscience 29 (47), 14881-14890, 2009 | 184 | 2009 |
Cardiovascular dysfunction following spinal cord injury E Partida, E Mironets, S Hou, VJ Tom Neural regeneration research 11 (2), 189-194, 2016 | 121 | 2016 |
Administration of chondroitinase ABC rostral or caudal to a spinal cord injury site promotes anatomical but not functional plasticity VJ Tom, R Kadakia, L Santi, JD Houlé Journal of neurotrauma 26 (12), 2323-2333, 2009 | 121 | 2009 |
Intraspinal microinjection of chondroitinase ABC following injury promotes axonal regeneration out of a peripheral nerve graft bridge VJ Tom, JD Houlé Experimental neurology 211 (1), 315-319, 2008 | 99 | 2008 |
Peripheral nerve grafts support regeneration after spinal cord injury MP Côté, AA Amin, VJ Tom, JD Houle Neurotherapeutics 8 (2), 294-303, 2011 | 84 | 2011 |
Local delivery of minocycline from metal ion-assisted self-assembled complexes promotes neuroprotection and functional recovery after spinal cord injury Z Wang, J Nong, RB Shultz, Z Zhang, T Kim, VJ Tom, RK Ponnappan, ... Biomaterials 112, 62-71, 2017 | 78 | 2017 |
Exogenous BDNF enhances the integration of chronically injured axons that regenerate through a peripheral nerve grafted into a chondroitinase-treated spinal cord injury site VJ Tom, HR Sandrow-Feinberg, K Miller, C Domitrovich, J Bouyer, ... Experimental neurology 239, 91-100, 2013 | 74 | 2013 |
Partial restoration of cardiovascular function by embryonic neural stem cell grafts after complete spinal cord transection S Hou, VJ Tom, L Graham, P Lu, A Blesch Journal of Neuroscience 33 (43), 17138-17149, 2013 | 73 | 2013 |
Expressing constitutively active rheb in adult neurons after a complete spinal cord injury enhances axonal regeneration beyond a chondroitinase-treated glial scar D Wu, MC Klaw, T Connors, N Kholodilov, RE Burke, VJ Tom Journal of Neuroscience 35 (31), 11068-11080, 2015 | 69 | 2015 |
Soluble TNFα signaling within the spinal cord contributes to the development of autonomic dysreflexia and ensuing vascular and immune dysfunction after spinal cord injury E Mironets, P Osei-Owusu, V Bracchi-Ricard, R Fischer, EA Owens, ... Journal of Neuroscience 38 (17), 4146-4162, 2018 | 53 | 2018 |
Expressing constitutively active Rheb in adult dorsal root ganglion neurons enhances the integration of sensory axons that regenerate across a chondroitinase-treated dorsal … D Wu, MC Klaw, N Kholodilov, RE Burke, MR Detloff, MP Côté, VJ Tom Frontiers in Molecular Neuroscience 9, 49, 2016 | 43 | 2016 |
Dopamine is produced in the rat spinal cord and regulates micturition reflex after spinal cord injury S Hou, DM Carson, D Wu, MC Klaw, JD Houlé, VJ Tom Experimental neurology 285, 136-146, 2016 | 42 | 2016 |
Knockdown of fidgetin improves regeneration of injured axons by a microtubule-based mechanism AJ Matamoros, VJ Tom, D Wu, Y Rao, DJ Sharp, PW Baas Journal of Neuroscience 39 (11), 2011-2024, 2019 | 37 | 2019 |
Intraspinal AAV injections immediately rostral to a thoracic spinal cord injury site efficiently transduces neurons in spinal cord and brain MC Klaw, C Xu, VJ Tom Molecular Therapy-Nucleic Acids 2, 2013 | 35 | 2013 |
Chronic neuronal activation increases dynamic microtubules to enhance functional axon regeneration after dorsal root crush injury D Wu, Y Jin, TM Shapiro, A Hinduja, PW Baas, VJ Tom Nature communications 11 (1), 6131, 2020 | 33 | 2020 |
Either brain-derived neurotrophic factor or neurotrophin-3 only neurotrophin-producing grafts promote locomotor recovery in untrained spinalized cats K Ollivier-Lanvin, I Fischer, V Tom, JD Houlé, MA Lemay Neurorehabilitation and Neural Repair 29 (1), 90-100, 2015 | 32 | 2015 |