Proteases and protease inhibitors in infectious diseases AA Agbowuro, WM Huston, AB Gamble, JDA Tyndall Medicinal research reviews 38 (4), 1295-1331, 2018 | 183 | 2018 |
Bioorthogonal prodrug activation driven by a strain-promoted 1, 3-dipolar cycloaddition SS Matikonda, DL Orsi, V Staudacher, IA Jenkins, F Fiedler, J Chen, ... Chemical Science 6 (2), 1212-1218, 2015 | 139 | 2015 |
Aryl nitro reduction with iron powder or stannous chloride under ultrasonic irradiation AB Gamble, J Garner, CP Gordon, SMJ O'Conner, PA Keller Synthetic Communications 37 (16), 2777-2786, 2007 | 122 | 2007 |
Controlled delivery of nitric oxide for cancer therapy H Alimoradi, K Greish, AB Gamble, GI Giles Pharmaceutical nanotechnology 7 (4), 279-303, 2019 | 88 | 2019 |
Hypoxia responsive drug delivery systems in tumor therapy H Alimoradi, S S Matikonda, A B Gamble, G I Giles, K Greish Current pharmaceutical design 22 (19), 2808-2820, 2016 | 41 | 2016 |
Poloxamer 407‐chitosan grafted thermoresponsive hydrogels achieve synchronous and sustained release of antigen and adjuvant from single‐shot vaccines S Bobbala, B Gibson, AB Gamble, A McDowell, S Hook Immunology and cell biology 96 (6), 656-665, 2018 | 39 | 2018 |
Mechanistic Evaluation of Bioorthogonal Decaging with trans-Cyclooctene: The Effect of Fluorine Substituents on Aryl Azide Reactivity and Decaging from the 1,2,3 … SS Matikonda, JM Fairhall, F Fiedler, S Sanhajariya, RAJ Tucker, S Hook, ... Bioconjugate chemistry 29 (2), 324-334, 2018 | 37 | 2018 |
Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor ES Spencer, EJ Dale, AL Gommans, MT Rutledge, CT Vo, Y Nakatani, ... European journal of medicinal chemistry 93, 501-510, 2015 | 32 | 2015 |
Self-immolative linkers in prodrugs and antibody drug conjugates in cancer treatment VVSR Edupuganti, JDA Tyndall, AB Gamble Recent patents on anti-cancer drug discovery 16 (4), 479-497, 2021 | 17 | 2021 |
Synthesis of reaction-ready 6, 6′-biindole and 6, 6′-biisatin via palladium (ii)-catalysed intramolecular C–H functionalisation AB Gamble, PA Keller Chemical communications 46 (23), 4076-4078, 2010 | 17 | 2010 |
Alkene–Azide 1, 3‐Dipolar Cycloaddition as a Trigger for Ultrashort Peptide Hydrogel Dissolution S Dadhwal, JM Fairhall, SK Goswami, S Hook, AB Gamble Chemistry–An Asian Journal 14 (8), 1143-1150, 2019 | 15 | 2019 |
Activation of RyR2 by class I kinase inhibitors AD Chakraborty, LA Gonano, ML Munro, LJ Smith, C Thekkedam, ... British Journal of Pharmacology 176 (6), 773-786, 2019 | 15 | 2019 |
Honey reduces the metastatic characteristics of prostate cancer cell lines by promoting a loss of adhesion SDA Abel, S Dadhwal, AB Gamble, SK Baird PeerJ 6, e5115, 2018 | 13 | 2018 |
Optimization of peptide-based inhibitors targeting the HtrA serine protease in Chlamydia: Design, synthesis and biological evaluation of pyridone-based and N-Capping group … J Hwang, N Strange, MJA Phillips, AL Krause, A Heywood, AB Gamble, ... European journal of medicinal chemistry 224, 113692, 2021 | 12 | 2021 |
Stability, kinetic, and mechanistic investigation of 1, 8-self-immolative cinnamyl ether spacers for controlled release of phenols and generation of resonance and inductively … SS Matikonda, JM Fairhall, JDA Tyndall, S Hook, AB Gamble Organic letters 19 (3), 528-531, 2017 | 12 | 2017 |
Structure-activity analysis of peptidic Chlamydia HtrA inhibitors AA Agbowuro, J Hwang, E Peel, R Mazraani, A Springwald, JW Marsh, ... Bioorganic & Medicinal Chemistry 27 (18), 4185-4199, 2019 | 11 | 2019 |
Potent and selective inhibitors of human peptidylglycine α-amidating monooxygenase F Cao, AB Gamble, HK Kim, H Onagi, MJ Gresser, J Kerr, CJ Easton MedChemComm 2 (8), 760-763, 2011 | 11 | 2011 |
Tuning activation and self-immolative properties of the bioorthogonal alkene–azide click-and-release strategy JM Fairhall, M Murayasu, S Dadhwal, S Hook, AB Gamble Organic & Biomolecular Chemistry 18 (25), 4754-4762, 2020 | 10 | 2020 |
Prohormone-substrate peptide sequence recognition by peptidylglycine α-amidating monooxygenase and its reflection in increased glycolate inhibitor potency KM Morris, F Cao, H Onagi, TM Altamore, AB Gamble, CJ Easton Bioorganic & medicinal chemistry letters 22 (23), 7015-7018, 2012 | 10 | 2012 |
Development and assessment of novel all-in-one parenteral formulations with integrated anticoagulant properties for the concomitant delivery of 5-fluorouracil and calcium folinate JM Locke, TK Stutchbury, KL Vine, AB Gamble, PR Clingan, JB Bremner, ... Anti-cancer drugs 20 (9), 822-831, 2009 | 10 | 2009 |