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Karl Malcolm
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Advances in microbicide vaginal rings
RK Malcolm, KL Edwards, P Kiser, J Romano, TJ Smith
Antiviral research 88, S30-S39, 2010
2062010
Long-term, controlled release of the HIV microbicide TMC120 from silicone elastomer vaginal rings
RK Malcolm, AD Woolfson, CF Toner, RJ Morrow, SD McCullagh
Journal of Antimicrobial Chemotherapy 56 (5), 954-956, 2005
1882005
Safety and pharmacokinetics of dapivirine delivery from matrix and reservoir intravaginal rings to HIV-negative women
A Nel, S Smythe, K Young, K Malcolm, C McCoy, Z Rosenberg, J Romano
JAIDS Journal of Acquired Immune Deficiency Syndromes 51 (4), 416-423, 2009
1772009
Intravaginal ring delivery of the reverse transcriptase inhibitor TMC 120 as an HIV microbicide
AD Woolfson, RK Malcolm, RJ Morrow, CF Toner, SD McCullagh
International journal of pharmaceutics 325 (1-2), 82-89, 2006
1682006
Influence of silicone elastomer solubility and diffusivity on the in vitro release of drugs from intravaginal rings
K Malcolm, D Woolfson, J Russell, P Tallon, L McAuley, D Craig
Journal of Controlled Release 90 (2), 217-225, 2003
1662003
Drug delivery by the intravaginal route
AD Woolfson, RK Malcolm, R Gallagher
Critical Reviews™ in Therapeutic Drug Carrier Systems 17 (5), 2000
1632000
Intravaginal drug delivery devices for the administration of an antimicrobial agent
K Malcolm, D Woolfson, G Elliott, M Shephard
US Patent 6,951,654, 2005
1412005
Intravaginal drug delivery devices for the delivery of macromolecules and water-soluble drugs
DA Woolfson, K Malcolm
US Patent 8,962,010, 2015
1142015
Microbicide vaginal rings: Technological challenges and clinical development
RK Malcolm, PJ Boyd, CF McCoy, DJ Murphy
Advanced drug delivery reviews 103, 33-56, 2016
1062016
Dual functional ionic liquids as plasticisers and antimicrobial agents for medical polymers
SY Choi, H Rodríguez, A Mirjafari, DF Gilpin, S McGrath, KR Malcolm, ...
Green Chemistry 13 (6), 1527-1535, 2011
1012011
Vaginal rings for delivery of HIV microbicides
RK Malcolm, SM Fetherston, CF McCoy, P Boyd, I Major
International Journal of Women's Health, 595-605, 2012
992012
Design of a silicone reservoir intravaginal ring for the delivery of oxybutynin
AD Woolfson, RK Malcolm, RJ Gallagher
Journal of controlled release 91 (3), 465-476, 2003
982003
A silicone elastomer vaginal ring for HIV prevention containing two microbicides with different mechanisms of action
SM Fetherston, P Boyd, CF McCoy, MC McBride, KL Edwards, S Ampofo, ...
European journal of pharmaceutical sciences 48 (3), 406-415, 2013
972013
Controlled release of a model antibacterial drug from a novel self-lubricating silicone biomaterial
RK Malcolm, SD McCullagh, AD Woolfson, SP Gorman, DS Jones, ...
Journal of controlled release 97 (2), 313-320, 2004
952004
Characterization of the rheological, mucoadhesive, and drug release properties of highly structured gel platforms for intravaginal drug delivery
GP Andrews, L Donnelly, DS Jones, RM Curran, RJ Morrow, AD Woolfson, ...
Biomacromolecules 10 (9), 2427-2435, 2009
892009
Pharmacokinetics and efficacy of a vaginally administered maraviroc gel in rhesus macaques
RK Malcolm, CJ Forbes, L Geer, RS Veazey, L Goldman, P Johan Klasse, ...
Journal of antimicrobial chemotherapy 68 (3), 678-683, 2013
862013
Microneedle mediated intradermal delivery of adjuvanted recombinant HIV-1 CN54gp140 effectively primes mucosal boost inoculations
A Pattani, PF McKay, MJ Garland, RM Curran, K Migalska, CM Cassidy, ...
Journal of controlled release 162 (3), 529-537, 2012
862012
High speed DSC (hyper-DSC) as a tool to measure the solubility of a drug within a solid or semi-solid matrix
D Gramaglia, BR Conway, VL Kett, RK Malcolm, HK Batchelor
International journal of pharmaceutics 301 (1-2), 1-5, 2005
842005
Sustained release of the CCR5 inhibitors CMPD167 and maraviroc from vaginal rings in rhesus macaques
RK Malcolm, RS Veazey, L Geer, D Lowry, SM Fetherston, DJ Murphy, ...
Antimicrobial agents and chemotherapy 56 (5), 2251-2258, 2012
812012
In vitro release of nonoxynol-9 from silicone matrix intravaginal rings
K Malcolm, D Woolfson, J Russell, C Andrews
Journal of Controlled Release 91 (3), 355-364, 2003
732003
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