mathy froeyen
mathy froeyen
Vahvistettu sähköpostiosoite verkkotunnuksessa
Cyclohexene nucleic acids (CeNA): serum stable oligonucleotides that activate RNase H and increase duplex stability with complementary RNA
J Wang, B Verbeure, I Luyten, E Lescrinier, M Froeyen, C Hendrix, ...
Journal of the American Chemical Society 122 (36), 8595-8602, 2000
Carbohydrate-binding agents cause deletions of highly conserved glycosylation sites in HIV gp120 A new therapeutic concept to hit the Achilles heel of HIV
J Balzarini, K Van Laethem, S Hatse, M Froeyen, W Peumans, ...
Journal of Biological Chemistry 280 (49), 41005-41014, 2005
Novel inhibitors of influenza virus fusion: structure-activity relationship and interaction with the viral hemagglutinin
E Vanderlinden, F Göktaş, Z Cesur, M Froeyen, ML Reed, CJ Russell, ...
Journal of virology 84 (9), 4277-4288, 2010
Molecular dynamics simulation of polarizable water by an extended Lagrangian method
D Van Belle, M Froeyen, G Lippens, SJ Wodak
Molecular physics 77 (2), 239-255, 1992
Mutations in the chikungunya virus non-structural proteins cause resistance to favipiravir (T-705), a broad-spectrum antiviral
L Delang, N Segura Guerrero, A Tas, G Quérat, B Pastorino, M Froeyen, ...
Journal of Antimicrobial Chemotherapy 69 (10), 2770-2784, 2014
Deoxythreosyl phosphonate nucleosides as selective anti-HIV agents
T Wu, M Froeyen, V Kempeneers, C Pannecouque, J Wang, R Busson, ...
Journal of the American Chemical Society 127 (14), 5056-5065, 2005
The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine
J Wang, M Froeyen, C Hendrix, G Andrei, R Snoeck, E De Clercq, ...
Journal of medicinal chemistry 43 (4), 736-745, 2000
Rational Design of 5 ‘-Thiourea-Substituted α-Thymidine Analogues as Thymidine Monophosphate Kinase Inhibitors Capable of Inhibiting Mycobacterial Growth
I Van Daele, H Munier-Lehmann, M Froeyen, J Balzarini, ...
Journal of medicinal chemistry 50 (22), 5281-5292, 2007
Reverse transcriptase incorporation of 1, 5-anhydrohexitol nucleotides
K Vastmans, M Froeyen, L Kerremans, S Pochet, P Herdewijn
Nucleic acids research 29 (15), 3154-3163, 2001
Marked depletion of glycosylation sites in HIV-1 gp120 under selection pressure by the mannose-specific plant lectins of Hippeastrum hybrid and Galanthus nivalis
J Balzarini, K Van Laethem, S Hatse, M Froeyen, E Van Damme, ...
Molecular pharmacology 67 (5), 1556-1565, 2005
A novel, highly selective inhibitor of pestivirus replication that targets the viral RNA-dependent RNA polymerase
J Paeshuyse, P Leyssen, E Mabery, N Boddeker, R Vrancken, M Froeyen, ...
Journal of virology 80 (1), 149-160, 2006
3‘-C-Branched-Chain-Substituted Nucleosides and Nucleotides as Potent Inhibitors of Mycobacterium tuberculosis Thymidine Monophosphate Kinase
V Vanheusden, H Munier-Lehmann, M Froeyen, L Dugué, A Heyerick, ...
Journal of medicinal chemistry 46 (18), 3811-3821, 2003
A derivate of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro
SJF Kaptein, T De Burghgraeve, M Froeyen, B Pastorino, MMF Alen, ...
Antimicrobial agents and chemotherapy 54 (12), 5269-5280, 2010
Translational properties of mHNA, a messenger RNA containing anhydrohexitol nucleotides
IN Lavrik, ON Avdeeva, OA Dontsova, M Froeyen, PA Herdewijn
Biochemistry 40 (39), 11777-11784, 2001
Difference in conformational diversity between nucleic acids with a six‐membered ‘sugar’unit and natural ‘furanose’nucleic acids
E Lescrinier, M Froeyen, P Herdewijn
Nucleic acids research 31 (12), 2975-2989, 2003
Discovery of Bicyclic Thymidine Analogues as Selective and High-Affinity Inhibitors of Mycobacterium tuberculosis Thymidine Monophosphate Kinase
V Vanheusden, H Munier-Lehmann, M Froeyen, R Busson, J Rozenski, ...
Journal of medicinal chemistry 47 (25), 6187-6194, 2004
Comparative study of the genetic barriers and pathways towards resistance of selective inhibitors of hepatitis C virus replication
L Delang, I Vliegen, M Froeyen, J Neyts
Antimicrobial agents and chemotherapy 55 (9), 4103-4113, 2011
Polymerase-catalyzed synthesis of DNA from phosphoramidate conjugates of deoxynucleotides and amino acids
O Adelfinskaya, M Terrazas, M Froeyen, P Marlière, K Nauwelaerts, ...
Nucleic acids research 35 (15), 5060-5072, 2007
Determination of the excited-state lifetimes of the tryptophan residues in barnase, via multifrequency phase fluorometry of tryptophan mutants
K Willaert, R Loewenthal, J Sancho, M Froeyen, A Fersht, Y Engelborghs
Biochemistry 31 (3), 711-716, 1992
Investigation of the DNA-dependent cyclohexenyl nucleic acid polymerization and the cyclohexenyl nucleic acid-dependent DNA polymerization
V Kempeneers, M Renders, M Froeyen, P Herdewijn
Nucleic acids research 33 (12), 3828-3836, 2005
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Artikkelit 1–20