| The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors SB Willingham, JP Volkmer, AJ Gentles, D Sahoo, P Dalerba, SS Mitra, ... Proceedings of the National Academy of Sciences 109 (17), 6662-6667, 2012 | 1589 | 2012 |
| Single-cell transcriptional diversity is a hallmark of developmental potential GS Gulati, SS Sikandar, DJ Wesche, A Manjunath, A Bharadwaj, ... Science 367 (6476), 405-411, 2020 | 574 | 2020 |
| Generation of stable monoclonal antibody–producing B cell receptor–positive human memory B cells by genetic programming MJ Kwakkenbos, SA Diehl, E Yasuda, AQ Bakker, CMM Van Geelen, ... Nature medicine 16 (1), 123-128, 2010 | 382 | 2010 |
| The CD47-SIRPα immune checkpoint MEW Logtenberg, FA Scheeren, TN Schumacher Immunity 52 (5), 742-752, 2020 | 345 | 2020 |
| STAT3-mediated up-regulation of BLIMP1 Is coordinated with BCL6 down-regulation to control human plasma cell differentiation SA Diehl, H Schmidlin, M Nagasawa, SD van Haren, MJ Kwakkenbos, ... The Journal of Immunology 180 (7), 4805-4815, 2008 | 305 | 2008 |
| Identification of a cKit+ colonic crypt base secretory cell that supports Lgr5+ stem cells in mice ME Rothenberg, Y Nusse, T Kalisky, JJ Lee, P Dalerba, F Scheeren, ... Gastroenterology 142 (5), 1195-1205. e6, 2012 | 304 | 2012 |
| Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer HE Kohrt, R Houot, K Weiskopf, MJ Goldstein, F Scheeren, D Czerwinski, ... The Journal of clinical investigation 122 (3), 1066-1075, 2012 | 280 | 2012 |
| STAT5 regulates the self-renewal capacity and differentiation of human memory B cells and controls Bcl-6 expression FA Scheeren, M Naspetti, S Diehl, R Schotte, M Nagasawa, E Wijnands, ... Nature immunology 6 (3), 303-313, 2005 | 257 | 2005 |
| A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19ARF–p53 signaling A Shvarts, TR Brummelkamp, F Scheeren, E Koh, GQ Daley, H Spits, ... Genes & development 16 (6), 681-686, 2002 | 210 | 2002 |
| miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway T Isobe, S Hisamori, DJ Hogan, M Zabala, DG Hendrickson, P Dalerba, ... Elife 3, e01977, 2014 | 182 | 2014 |
| IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis FA Scheeren, SA Diehl, LA Smit, T Beaumont, M Naspetti, RJ Bende, ... Blood, The Journal of the American Society of Hematology 111 (9), 4706-4715, 2008 | 171 | 2008 |
| Glutaminyl cyclase is an enzymatic modifier of the CD47-SIRPα axis and a target for cancer immunotherapy MEW Logtenberg, JHM Jansen, M Raaben, M Toebes, K Franke, ... Nature medicine 25 (4), 612-619, 2019 | 166 | 2019 |
| T cell–independent development and induction of somatic hypermutation in human IgM+IgD+CD27+ B cells FA Scheeren, M Nagasawa, K Weijer, T Cupedo, J Kirberg, N Legrand, ... The Journal of experimental medicine 205 (9), 2033-2042, 2008 | 131 | 2008 |
| A cell-intrinsic role for TLR2–MYD88 in intestinal and breast epithelia and oncogenesis FA Scheeren, AH Kuo, LJ Van Weele, S Cai, I Glykofridis, SS Sikandar, ... Nature cell biology 16 (12), 1238-1248, 2014 | 125 | 2014 |
| Targeting unique metabolic properties of breast tumor initiating cells W Feng, A Gentles, RV Nair, M Huang, Y Lin, CY Lee, S Cai, FA Scheeren, ... Stem cells 32 (7), 1734-1745, 2014 | 119 | 2014 |
| Delta-like1-induced Notch1 signaling regulates the human plasmacytoid dendritic cell versus T-cell lineage decision through control of GATA-3 and Spi-B W Dontje, R Schotte, T Cupedo, M Nagasawa, F Scheeren, R Gimeno, ... Blood 107 (6), 2446-2452, 2006 | 119 | 2006 |
| A nonpeptidic cathepsin S activity-based probe for noninvasive optical imaging of tumor-associated macrophages M Verdoes, LE Edgington, FA Scheeren, M Leyva, G Blum, K Weiskopf, ... Chemistry & biology 19 (5), 619-628, 2012 | 117 | 2012 |
| CD14-expressing cancer cells establish the inflammatory and proliferative tumor microenvironment in bladder cancer MT Cheah, JY Chen, D Sahoo, H Contreras-Trujillo, AK Volkmer, ... Proceedings of the National Academy of Sciences 112 (15), 4725-4730, 2015 | 106 | 2015 |
| Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression H Schmidlin, SA Diehl, M Nagasawa, FA Scheeren, R Schotte, ... Blood, The Journal of the American Society of Hematology 112 (5), 1804-1812, 2008 | 99 | 2008 |
| Generation of human antigen-specific monoclonal IgM antibodies using vaccinated “human immune system” mice PD Becker, N Legrand, CMM van Geelen, M Noerder, ND Huntington, ... PloS one 5 (10), e13137, 2010 | 98 | 2010 |
Hergen SpitsAcademic Medical Centre, and AIMM therapeutics, AmsterdamVerified email at amc.uva.nl
