Isaac Kohane
Isaac Kohane
Harvard Medical School, Children's Hospital, Brigham and Women's Hospital
Verified email at - Homepage
Cited by
Cited by
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
Cancer Genome Atlas (TCGA) Research Network
Nature 455 (7216), 1061, 2008
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1
ME Patti, AJ Butte, S Crunkhorn, K Cusi, R Berria, S Kashyap, Y Miyazaki, ...
Proceedings of the National Academy of Sciences 100 (14), 8466-8471, 2003
Gene regulation and DNA damage in the ageing human brain
T Lu, Y Pan, SY Kao, C Li, I Kohane, J Chan, BA Yankner
Nature 429 (6994), 883-891, 2004
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668-681, 2018
Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements
AJ Butte, IS Kohane
Biocomputing 2000, 418-429, 1999
A mega-analysis of genome-wide association studies for major depressive disorder
Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium
Molecular psychiatry 18 (4), 2013
A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers
SL Carter, AC Eklund, IS Kohane, LN Harris, Z Szallasi
Nature genetics 38 (9), 1043-1048, 2006
Toward precision medicine: building a knowledge network for biomedical research and a new taxonomy of disease
National Research Council
National Academies Press, 2011
Machine learning in medicine
A Rajkomar, J Dean, I Kohane
New England Journal of Medicine 380 (14), 1347-1358, 2019
Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)
SN Murphy, G Weber, M Mendis, V Gainer, HC Chueh, S Churchill, ...
Journal of the American Medical Informatics Association 17 (2), 124-130, 2010
Big data and machine learning in health care
AL Beam, IS Kohane
Jama 319 (13), 1317-1318, 2018
Discovering statistically significant pathways in expression profiling studies
L Tian, SA Greenberg, SW Kong, J Altschuler, IS Kohane, PJ Park
Proceedings of the National Academy of Sciences 102 (38), 13544-13549, 2005
Discovering functional relationships between RNA expression and chemotherapeutic susceptibility using relevance networks
AJ Butte, P Tamayo, D Slonim, TR Golub, IS Kohane
Proceedings of the National Academy of Sciences 97 (22), 12182-12186, 2000
Artificial intelligence in healthcare
KH Yu, AL Beam, IS Kohane
Nature biomedical engineering 2 (10), 719-731, 2018
Analysis of matched mRNA measurements from two different microarray technologies
WP Kuo, TK Jenssen, AJ Butte, L Ohno-Machado, IS Kohane
Bioinformatics 18 (3), 405-412, 2002
Human disease classification in the postgenomic era: a complex systems approach to human pathobiology
J Loscalzo, I Kohane, AL Barabasi
Molecular systems biology 3 (1), 124, 2007
Distinctive patterns of microRNA expression in primary muscular disorders
I Eisenberg, A Eran, I Nishino, M Moggio, C Lamperti, AA Amato, ...
Proceedings of the National Academy of Sciences 104 (43), 17016-17021, 2007
Cluster analysis of gene expression dynamics
MF Ramoni, P Sebastiani, IS Kohane
Proceedings of the National Academy of Sciences 99 (14), 9121-9126, 2002
The co-morbidity burden of children and young adults with autism spectrum disorders
IS Kohane, A McMurry, G Weber, D MacFadden, L Rappaport, L Kunkel, ...
PloS one 7 (4), e33224, 2012
Public standards and patients' control: how to keep electronic medical records accessible but privateMedical information: access and privacyDoctrines for developing electronic …
KD Mandl, D Markwell, R MacDonald, P Szolovits, IS Kohane
Bmj 322 (7281), 283-287, 2001
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