| PAX3–FOXO1 establishes myogenic super enhancers and confers BET bromodomain vulnerability BE Gryder, ME Yohe, HC Chou, X Zhang, J Marques, M Wachtel, ... Cancer Discovery 7 (8), 884-899, 2017 | 250 | 2017 |
| ARF GTPases and their GEFs and GAPs: concepts and challenges E Sztul, PW Chen, JE Casanova, J Cherfils, JB Dacks, DG Lambright, ... Molecular biology of the cell 30 (11), 1249-1271, 2019 | 196 | 2019 |
| Gαq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain RJ Rojas, ME Yohe, S Gershburg, T Kawano, T Kozasa, J Sondek Journal of biological chemistry 282 (40), 29201-29210, 2007 | 169 | 2007 |
| MEK inhibition induces MYOG and remodels super-enhancers in RAS-driven rhabdomyosarcoma ME Yohe, BE Gryder, JF Shern, YK Song, HC Chou, S Sindiri, A Mendoza, ... Science translational medicine 10 (448), eaan4470, 2018 | 124 | 2018 |
| Chemical genomics reveals histone deacetylases are required for core regulatory transcription BE Gryder, L Wu, GM Woldemichael, S Pomella, TR Quinn, PMC Park, ... Nature communications 10 (1), 3004, 2019 | 123 | 2019 |
| Genomic classification and clinical outcome in rhabdomyosarcoma: a report from an international consortium JF Shern, J Selfe, E Izquierdo, R Patidar, HC Chou, YK Song, ME Yohe, ... Journal of Clinical Oncology 39 (26), 2859, 2021 | 114 | 2021 |
| Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression N Mitin, L Betts, ME Yohe, CJ Der, J Sondek, KL Rossman Nature structural & molecular biology 14 (9), 814-823, 2007 | 111 | 2007 |
| MultiDimensional ClinOmics for precision therapy of children and adolescent young adults with relapsed and refractory cancer: a report from the center for cancer research W Chang, AS Brohl, R Patidar, S Sindiri, JF Shern, JS Wei, YK Song, ... Clinical cancer research 22 (15), 3810-3820, 2016 | 107 | 2016 |
| Fatty acid synthase expression is induced by the Epstein-Barr virus immediate-early protein BRLF1 and is required for lytic viral gene expression Y Li, J Webster-Cyriaque, CC Tomlinson, M Yohe, S Kenney Journal of virology 78 (8), 4197-4206, 2004 | 105 | 2004 |
| Pediatric rhabdomyosarcoma JF Shern, ME Yohe, J Khan Critical Reviews™ in Oncogenesis 20 (3-4), 2015 | 100 | 2015 |
| Targeting glycolysis through inhibition of lactate dehydrogenase impairs tumor growth in preclinical models of Ewing sarcoma C Yeung, AE Gibson, SH Issaq, N Oshima, JT Baumgart, LD Edessa, ... Cancer research 79 (19), 5060-5073, 2019 | 97 | 2019 |
| Insights into pediatric rhabdomyosarcoma research: Challenges and goals ME Yohe, CM Heske, E Stewart, PC Adamson, N Ahmed, CR Antonescu, ... Pediatric blood & cancer 66 (10), e27869, 2019 | 71 | 2019 |
| Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma IM Tenente, MN Hayes, MS Ignatius, K McCarthy, M Yohe, S Sindiri, ... Elife 6, e19214, 2017 | 68 | 2017 |
| Clonality and evolutionary history of rhabdomyosarcoma L Chen, JF Shern, JS Wei, ME Yohe, YK Song, L Hurd, H Liao, ... PLoS genetics 11 (3), e1005075, 2015 | 65 | 2015 |
| Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma D Bogen, JS Wei, DO Azorsa, P Ormanoglu, E Buehler, R Guha, JM Keller, ... Oncotarget 6 (34), 35247, 2015 | 58 | 2015 |
| Molecular basis for cooperative binding of anionic phospholipids to the PH domain of the Arf GAP ASAP1 X Jian, WK Tang, P Zhai, NS Roy, R Luo, JM Gruschus, ME Yohe, ... Structure 23 (11), 1977-1988, 2015 | 58 | 2015 |
| Auto-inhibition of the Dbl family protein Tim by an N-terminal helical motif ME Yohe, KL Rossman, OS Gardner, AE Karnoub, JT Snyder, ... Journal of biological chemistry 282 (18), 13813-13823, 2007 | 57 | 2007 |
| The RASopathies: from pathogenetics to therapeutics KE Hebron, ER Hernandez, ME Yohe Disease models & mechanisms 15 (2), dmm049107, 2022 | 56 | 2022 |
| Role of the C-terminal SH3 domain and N-terminal tyrosine phosphorylation in regulation of Tim and related Dbl-family proteins ME Yohe, K Rossman, J Sondek Biochemistry 47 (26), 6827-6839, 2008 | 48 | 2008 |
| MDS-associated mutations in germline GATA2 mutated patients with hematologic manifestations LJ McReynolds, Y Yang, HY Wong, J Tang, Y Zhang, MP Mulé, J Daub, ... Leukemia research 76, 70-75, 2019 | 46 | 2019 |
Javed KhanDeputy Branch Chief Genetics Branch, Senior Investigator, Center for Cancer Research, NCI, NIHVerified email at mail.nih.gov
