| FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation M Welcker, BE Clurman Nature Reviews Cancer 8 (2), 83-93, 2008 | 1203 | 2008 |
| Rapid destruction of human Cdc25A in response to DNA damage N Mailand, J Falck, C Lukas, RG Syljuåsen, M Welcker, J Bartek, J Lukas Science 288 (5470), 1425-1429, 2000 | 1075 | 2000 |
| The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation M Welcker, A Orian, J Jin, JA Grim, JW Harper, RN Eisenman, ... Proceedings of the National Academy of Sciences 101 (24), 9085-9090, 2004 | 1027 | 2004 |
| FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors J O'Neil, J Grim, P Strack, S Rao, D Tibbitts, C Winter, J Hardwick, ... The Journal of experimental medicine 204 (8), 1813-1824, 2007 | 790 | 2007 |
| Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation M Welcker, J Singer, KR Loeb, J Grim, A Bloecher, M Gurien-West, ... Molecular cell 12 (2), 381-392, 2003 | 474 | 2003 |
| A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size M Welcker, A Orian, JA Grim, RN Eisenman, BE Clurman Current Biology 14 (20), 1852-1857, 2004 | 368 | 2004 |
| Tumor suppression by the Fbw7 ubiquitin ligase: mechanisms and opportunities RJ Davis, M Welcker, BE Clurman Cancer cell 26 (4), 455-464, 2014 | 365 | 2014 |
| Kinase-independent function of cyclin E Y Geng, YM Lee, M Welcker, J Swanger, A Zagozdzon, JD Winer, ... Molecular cell 25 (1), 127-139, 2007 | 216 | 2007 |
| Identification of CDK2 substrates in human cell lysates Y Chi, M Welcker, AA Hizli, JJ Posakony, R Aebersold, BE Clurman Genome biology 9, 1-12, 2008 | 191 | 2008 |
| Fbw7/hCDC4 dimerization regulates its substrate interactions M Welcker, BE Clurman Cell division 2, 1-13, 2007 | 153 | 2007 |
| Recognition of phosphodegron motifs in human cyclin E by the SCFFbw7 ubiquitin ligase X Ye, G Nalepa, M Welcker, BM Kessler, E Spooner, J Qin, SJ Elledge, ... Journal of Biological Chemistry 279 (48), 50110-50119, 2004 | 153 | 2004 |
| p53 and p21 form an inducible barrier that protects cells against cyclin E-cdk2 deregulation AC Minella, J Swanger, E Bryant, M Welcker, H Hwang, BE Clurman Current Biology 12 (21), 1817-1827, 2002 | 148 | 2002 |
| Cyclin D2 is a moderately oscillating nucleoprotein required for G1 phase progression in specific cell types. J Lukas, J Bartkova, M Welcker, OW Petersen, G Peters, M Strauss, ... Oncogene 10 (11), 2125-2134, 1995 | 147 | 1995 |
| Isoform-and cell cycle–dependent substrate degradation by the Fbw7 ubiquitin ligase JE Grim, MP Gustafson, RK Hirata, AC Hagar, J Swanger, M Welcker, ... The Journal of cell biology 181 (6), 913-920, 2008 | 135 | 2008 |
| Fbw7 dimerization determines the specificity and robustness of substrate degradation M Welcker, EA Larimore, J Swanger, MT Bengoechea-Alonso, JE Grim, ... Genes & development 27 (23), 2531-2536, 2013 | 110 | 2013 |
| Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo AC Minella, KR Loeb, A Knecht, M Welcker, BJ Varnum-Finney, ... Genes & development 22 (12), 1677-1689, 2008 | 107 | 2008 |
| The SV40 Large T Antigen Contains a Decoy Phosphodegron That Mediates Its Interactions with Fbw7/hCdc4*♦ M Welcker, BE Clurman Journal of Biological Chemistry 280 (9), 7654-7658, 2005 | 105 | 2005 |
| Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A–cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase AA Hizli, Y Chi, J Swanger, JH Carter, Y Liao, M Welcker, AG Ryazanov, ... Molecular and cellular biology, 2013 | 102 | 2013 |
| Ras activity regulates cyclin E degradation by the Fbw7 pathway AC Minella, M Welcker, BE Clurman Proceedings of the National Academy of Sciences 102 (27), 9649-9654, 2005 | 79 | 2005 |
| Enhanced protein stability: a novel mechanism of D-type cyclin over-abundance identified in human sarcoma cells. M Welcker, J Lukas, M Strauss, J Bartek Oncogene 13 (2), 419-425, 1996 | 71 | 1996 |
