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Shu Yi Shen
Shu Yi Shen
University Health Network
Verified email at uhnresearch.ca
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Cited by
Cited by
Year
DNA-demethylating agents target colorectal cancer cells by inducing viral mimicry by endogenous transcripts
D Roulois, HL Yau, R Singhania, Y Wang, A Danesh, SY Shen, H Han, ...
Cell 162 (5), 961-973, 2015
12562015
Sensitive tumour detection and classification using plasma cell-free DNA methylomes
SY Shen, R Singhania, G Fehringer, A Chakravarthy, MHA Roehrl, ...
Nature 563 (7732), 579-583, 2018
7012018
Detection of renal cell carcinoma using plasma and urine cell-free DNA methylomes
PV Nuzzo, JE Berchuck, K Korthauer, S Spisak, AH Nassar, S Abou Alaiwi, ...
Nature medicine 26 (7), 1041-1043, 2020
2092020
Detection and discrimination of intracranial tumors using plasma cell-free DNA methylomes
F Nassiri, A Chakravarthy, S Feng, SY Shen, R Nejad, JA Zuccato, ...
Nature medicine 26 (7), 1044-1047, 2020
2082020
Mutant IDH1 downregulates ATM and alters DNA repair and sensitivity to DNA damage independent of TET2
S Inoue, WY Li, A Tseng, I Beerman, AJ Elia, SC Bendall, F Lemonnier, ...
Cancer cell 30 (2), 337-348, 2016
2062016
Preparation of cfMeDIP-seq libraries for methylome profiling of plasma cell-free DNA
SY Shen, JM Burgener, SV Bratman, DD De Carvalho
Nature protocols 14 (10), 2749-2780, 2019
1352019
Seasonal variation of bacterial endophytes in urban trees
SY Shen, R Fulthorpe
Frontiers in microbiology 6, 127068, 2015
932015
Bacterial endophytes isolated from plants in natural oil seep soils with chronic hydrocarbon contamination
R Lumactud, SY Shen, M Lau, R Fulthorpe
Frontiers in microbiology 7, 185762, 2016
742016
Tumor-naïve multimodal profiling of circulating tumor DNA in head and neck squamous cell carcinoma
JM Burgener, J Zou, Z Zhao, Y Zheng, SY Shen, SH Huang, S Keshavarzi, ...
Clinical Cancer Research 27 (15), 4230-4244, 2021
632021
DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells
HL Yau, E Bell, I Ettayebi, FC de Almeida, GM Boukhaled, SY Shen, ...
Molecular cell 81 (7), 1469-1483. e8, 2021
612021
An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors
K Taylor, HL Yau, A Chakravarthy, B Wang, SY Shen, I Ettayebi, CA Ishak, ...
Journal for immunotherapy of cancer 8 (2), 2020
432020
The cell-free DNA methylome captures distinctions between localized and metastatic prostate tumors
S Chen, J Petricca, W Ye, J Guan, Y Zeng, N Cheng, L Gong, SY Shen, ...
Nature communications 13 (1), 6467, 2022
302022
Modeling methyl-sensitive transcription factor motifs with an expanded epigenetic alphabet
C Viner, CA Ishak, J Johnson, NJ Walker, H Shi, MK Sjöberg-Herrera, ...
Genome biology 25 (1), 11, 2024
272024
Dynamics of the cell-free DNA methylome of metastatic prostate cancer during androgen-targeting treatment
MR Peter, M Bilenky, R Isserlin, GD Bader, SY Shen, DD De Carvalho, ...
Epigenomics 12 (15), 1317-1332, 2020
162020
Cerebrospinal fluid methylome-based liquid biopsies for accurate malignant brain neoplasm classification
JA Zuccato, V Patil, S Mansouri, M Voisin, A Chakravarthy, SY Shen, ...
Neuro-oncology 25 (8), 1452-1460, 2023
132023
Seasonal variation of bacterial endophytes in urban trees. Front Microbiol 6: 427
SY Shen, R Fulthorpe
122015
PacBio SMRT assembly of a complex multi-replicon genome reveals chlorocatechol degradative operon in a region of genome plasticity
N Ricker, SY Shen, J Goordial, S Jin, RR Fulthorpe
Gene 586 (2), 239-247, 2016
112016
Fungal endophytes increase biomass production in pale swallow-wort (Vincetoxicum rossicum (Kleopow) Barbar.)
RB Dickinson, RS Bourchier, RR Fulthorpe, SY Shen, IM Jones, SM Smith
Botany 99 (6), 337-353, 2021
52021
Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls
SL Wilson, SY Shen, L Harmon, JM Burgener, T Triche, SV Bratman, ...
Cell Reports Methods 2 (9), 2022
32022
Methods of capturing cell-free methylated dna and uses of same
DD De Carvalho, SY Shen, R Singhania
32017
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