Seuraa
James P Reddington
James P Reddington
Cellzome GmbH, a GSK company
Vahvistettu sähköpostiosoite verkkotunnuksessa gsk.com
Nimike
Viittaukset
Viittaukset
Vuosi
Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes
CE Nestor, R Ottaviano, J Reddington, D Sproul, D Reinhardt, D Dunican, ...
Genome research 22 (3), 467-477, 2012
4632012
The cis-regulatory dynamics of embryonic development at single-cell resolution
DA Cusanovich, JP Reddington, DA Garfield, RM Daza, D Aghamirzaie, ...
Nature 555 (7697), 538-542, 2018
3502018
Redistribution of H3K27me3 upon DNA hypomethylation results in de-repression of Polycomb target genes
JP Reddington, SM Perricone, CE Nestor, J Reichmann, NA Youngson, ...
Genome biology 14, 1-17, 2013
2602013
Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline
JA Hackett, JP Reddington, CE Nestor, DS Dunican, MR Branco, ...
Development 139 (19), 3623-3632, 2012
1732012
Non-canonical functions of the DNA methylome in gene regulation
JP Reddington, S Pennings, RR Meehan
Biochemical Journal 451 (1), 13-23, 2013
1052013
The non-methylated DNA-binding function of Kaiso is not required in early Xenopus laevis development
A Ruzov, E Savitskaya, JA Hackett, JP Reddington, A Prokhortchouk, ...
Oxford University Press for The Company of Biologists Limited 136 (5), 729-738, 2009
712009
The interaction of xKaiso with xTcf3: a revised model for integration of epigenetic and Wnt signalling pathways
A Ruzov, JA Hackett, A Prokhortchouk, JP Reddington, MJ Madej, ...
Oxford University Press for The Company of Biologists Limited 136 (5), 723-727, 2009
632009
The multifunctional poly (A)-binding protein (PABP) 1 is subject to extensive dynamic post-translational modification, which molecular modelling suggests plays an important …
M Brook, L McCracken, JP Reddington, ZL Lu, NA Morrice, NK Gray
Biochemical Journal 441 (3), 803-816, 2012
582012
Lineage-resolved enhancer and promoter usage during a time course of embryogenesis
JP Reddington, DA Garfield, OM Sigalova, AK Calviello, ...
Developmental cell 55 (5), 648-664. e9, 2020
482020
The genome-defence gene Tex19.1 suppresses LINE-1 retrotransposons in the placenta and prevents intra-uterine growth retardation in mice
J Reichmann, JP Reddington, D Best, D Read, R Öllinger, RR Meehan, ...
Human molecular genetics 22 (9), 1791-1806, 2013
482013
DNA methylation reprogramming in cancer: Does it act by re‐configuring the binding landscape of Polycomb repressive complexes?
JP Reddington, D Sproul, RR Meehan
Bioessays 36 (2), 134-140, 2014
432014
Apoptosis and DNA methylation
HX Meng, JA Hackett, C Nestor, DS Dunican, M Madej, JP Reddington, ...
Cancers 3 (2), 1798-1820, 2011
272011
The Role of Chromatin Accessibility in cis-Regulatory Evolution
PC Peng, P Khoueiry, C Girardot, JP Reddington, DA Garfield, ...
Genome biology and evolution 11 (7), 1813-1828, 2019
202019
Investigating 5-hydroxymethylcytosine (5hmC): the state of the art
CE Nestor, JP Reddington, M Benson, RR Meehan
Functional Analysis of DNA and Chromatin, 243-258, 2014
182014
The hourglass model of evolutionary conservation during embryogenesis extends to developmental enhancers with signatures of positive selection
J Liu, RR Viales, P Khoueiry, JP Reddington, C Girardot, EEM Furlong, ...
Genome research 31 (9), 1573-1581, 2021
152021
scDALI: modeling allelic heterogeneity in single cells reveals context-specific genetic regulation
T Heinen, S Secchia, JP Reddington, B Zhao, EEM Furlong, O Stegle
Genome biology 23 (1), 8, 2022
112022
DNA methylation in mammalian and non-mammalian organisms
M Moffat, JP Reddington, S Pennings, RR Meehan
DNA METHYLATION–FROM GENOMICS TO TECHNOLOGY, 119, 2012
22012
scDALI: Modelling allelic heterogeneity of DNA accessibility in single-cells reveals context-specific genetic regulation
T Heinen, S Secchia, J Reddington, B Zhao, EEM Furlong, O Stegle
bioRxiv, 2021.03. 19.436142, 2021
12021
Evolutionary changes in DNA accessibility and sequence predict divergence of transcription factor binding and enhancer activity
PC Peng, P Khoueiry, C Girardot, JP Reddington, DA Garfield, ...
bioRxiv, 319046, 2018
12018
Putting muscle in DNA methylation
JP Reddington, RR Meehan
Cell Research 21 (11), 1531-1533, 2011
12011
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Artikkelit 1–20