Assessing Myocardial Disease Using T MRI

Y Han, T Liimatainen, RC Gorman… - Current cardiovascular …, 2014 - Springer
There is great interest to use magnetic resonance imaging (MRI) for non-invasive assessment
of myocardial disease in ischemic and non-ischemic cardiomyopathies. Recently, there …

Non-invasive imaging in gene therapy

JK Räty, T Liimatainen, MU Kaikkonen, O Gröhn… - Molecular Therapy, 2007 - cell.com
Several methods are available for non-invasive imaging of gene delivery and transgene
expression, including magnetic resonance imaging (MRI), single photon emission tomography (…

Rhizavidin from Rhizobium etli: the first natural dimer in the avidin protein family

…, JP Slotte, T Huhtala, T Liimatainen… - Biochemical …, 2007 - portlandpress.com
Rhizobium etli CFN42 is a symbiotic nitrogen-fixing bacterium of the common bean Phaseolus
vulgaris. The symbiotic plasmid p42d of R. etli comprises a gene encoding a putative (…

Blood flow remodels growing vasculature during vascular endothelial growth factor gene therapy and determines between capillary arterialization and sprouting …

…, P Korpisalo, JE Markkanen, T Liimatainen… - Circulation, 2005 - Am Heart Assoc
Background— For clinically relevant proangiogenic therapy, it would be essential that the
growth of the whole vascular tree is promoted. Vascular endothelial growth factor (VEGF) is …

The SPECT imaging shows the accumulation of neural progenitor cells into internal organs after systemic administration in middle cerebral artery occlusion rats

…, S Narkilahti, T Huhtala, T Liimatainen… - Neuroscience …, 2008 - Elsevier
The regenerative potential of stem cells from various sources has been under intense
investigation in the experimental models of cerebral ischemia. To end up with a restorative …

MRI contrast from relaxation along a fictitious field (RAFF)

T Liimatainen, DJ Sorce, R O'Connell… - Magnetic resonance …, 2010 - Wiley Online Library
A new method to measure rotating frame relaxation and to create contrast for MRI is introduced.
The technique exploits relaxation along a fictitious field (RAFF) generated by amplitude‐ …

Molecular imaging of apoptosis in cancer

JM Hakumäki, T Liimatainen - European journal of radiology, 2005 - Elsevier
Apoptosis plays an important role in cancer. Mechanisms hindering its action are implicated
in a number of malignancies. Also, the induction of apoptosis plays a pivotal role in non-…

Rotating frame relaxation during adiabatic pulses vs. conventional spin lock: simulations and experimental results at 4 T

S Mangia, T Liimatainen, M Garwood… - Magnetic resonance …, 2009 - Elsevier
Spin relaxation taking place during radiofrequency (RF) irradiation can be assessed by
measuring the longitudinal and transverse rotating frame relaxation rate constants (R 1ρ and R …

Wall shear stress predicts media degeneration and biomechanical changes in thoracic aorta

…, ES Luoto, P Jaakkola, P Saari, T Liimatainen… - Frontiers in …, 2022 - frontiersin.org
Objectives: In thoracic aortic aneurysm (TAA) of the ascending aorta (AA), AA is progressively
dilating due to the weakening of the aortic wall. Predicting and preventing aortic …

Human umbilical cord blood cells do not improve sensorimotor or cognitive outcome following transient middle cerebral artery occlusion in rats

S Mäkinen, T Kekarainen, J Nystedt, T Liimatainen… - Brain research, 2006 - Elsevier
The present study investigated effects of human umbilical cord blood (HUCB) cells on
sensorimotor, cognitive, and histological outcome in rats subjected to transient middle cerebral …