Assessing Myocardial Disease Using T1ρ MRI
There is great interest to use magnetic resonance imaging (MRI) for non-invasive assessment
of myocardial disease in ischemic and non-ischemic cardiomyopathies. Recently, there …
of myocardial disease in ischemic and non-ischemic cardiomyopathies. Recently, there …
Non-invasive imaging in gene therapy
Several methods are available for non-invasive imaging of gene delivery and transgene
expression, including magnetic resonance imaging (MRI), single photon emission tomography (…
expression, including magnetic resonance imaging (MRI), single photon emission tomography (…
Rhizavidin from Rhizobium etli: the first natural dimer in the avidin protein family
…, JP Slotte, T Huhtala, T Liimatainen… - Biochemical …, 2007 - portlandpress.com
Rhizobium etli CFN42 is a symbiotic nitrogen-fixing bacterium of the common bean Phaseolus
vulgaris. The symbiotic plasmid p42d of R. etli comprises a gene encoding a putative (…
vulgaris. The symbiotic plasmid p42d of R. etli comprises a gene encoding a putative (…
Blood flow remodels growing vasculature during vascular endothelial growth factor gene therapy and determines between capillary arterialization and sprouting …
…, P Korpisalo, JE Markkanen, T Liimatainen… - Circulation, 2005 - Am Heart Assoc
Background— For clinically relevant proangiogenic therapy, it would be essential that the
growth of the whole vascular tree is promoted. Vascular endothelial growth factor (VEGF) is …
growth of the whole vascular tree is promoted. Vascular endothelial growth factor (VEGF) is …
The SPECT imaging shows the accumulation of neural progenitor cells into internal organs after systemic administration in middle cerebral artery occlusion rats
…, S Narkilahti, T Huhtala, T Liimatainen… - Neuroscience …, 2008 - Elsevier
The regenerative potential of stem cells from various sources has been under intense
investigation in the experimental models of cerebral ischemia. To end up with a restorative …
investigation in the experimental models of cerebral ischemia. To end up with a restorative …
MRI contrast from relaxation along a fictitious field (RAFF)
T Liimatainen, DJ Sorce, R O'Connell… - Magnetic resonance …, 2010 - Wiley Online Library
A new method to measure rotating frame relaxation and to create contrast for MRI is introduced.
The technique exploits relaxation along a fictitious field (RAFF) generated by amplitude‐ …
The technique exploits relaxation along a fictitious field (RAFF) generated by amplitude‐ …
Molecular imaging of apoptosis in cancer
JM Hakumäki, T Liimatainen - European journal of radiology, 2005 - Elsevier
Apoptosis plays an important role in cancer. Mechanisms hindering its action are implicated
in a number of malignancies. Also, the induction of apoptosis plays a pivotal role in non-…
in a number of malignancies. Also, the induction of apoptosis plays a pivotal role in non-…
Rotating frame relaxation during adiabatic pulses vs. conventional spin lock: simulations and experimental results at 4 T
S Mangia, T Liimatainen, M Garwood… - Magnetic resonance …, 2009 - Elsevier
Spin relaxation taking place during radiofrequency (RF) irradiation can be assessed by
measuring the longitudinal and transverse rotating frame relaxation rate constants (R 1ρ and R …
measuring the longitudinal and transverse rotating frame relaxation rate constants (R 1ρ and R …
Wall shear stress predicts media degeneration and biomechanical changes in thoracic aorta
…, ES Luoto, P Jaakkola, P Saari, T Liimatainen… - Frontiers in …, 2022 - frontiersin.org
Objectives: In thoracic aortic aneurysm (TAA) of the ascending aorta (AA), AA is progressively
dilating due to the weakening of the aortic wall. Predicting and preventing aortic …
dilating due to the weakening of the aortic wall. Predicting and preventing aortic …
Human umbilical cord blood cells do not improve sensorimotor or cognitive outcome following transient middle cerebral artery occlusion in rats
S Mäkinen, T Kekarainen, J Nystedt, T Liimatainen… - Brain research, 2006 - Elsevier
The present study investigated effects of human umbilical cord blood (HUCB) cells on
sensorimotor, cognitive, and histological outcome in rats subjected to transient middle cerebral …
sensorimotor, cognitive, and histological outcome in rats subjected to transient middle cerebral …